Detalhe da pesquisa
1.
High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Hum Mol Genet
; 26(5): 913-922, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334820
2.
Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
PLoS Genet
; 9(10): e1003930, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24204323
3.
Chromosome substitution strain assessment of a Huntington's disease modifier locus.
Mamm Genome
; 26(3-4): 119-30, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25645993
4.
Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice.
Elife
; 92020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32990597
5.
HttQ111/+ Huntington's Disease Knock-in Mice Exhibit Brain Region-Specific Morphological Changes and Synaptic Dysfunction.
J Huntingtons Dis
; 7(1): 17-33, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29480209
6.
Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
PLoS One
; 7(9): e44273, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970194
7.
Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
PLoS One
; 6(8): e23647, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21897851