Detalhe da pesquisa
1.
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.
PLoS Biol
; 18(7): e3000410, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663219
2.
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0.
PLoS Biol
; 18(7): e3000411, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663221
3.
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research.
J Physiol
; 598(18): 3793-3801, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666574
4.
The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments.
Nat Methods
; 19(11): 1334-1337, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36064774
5.
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.
Exp Physiol
; 105(9): 1459-1466, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666546
6.
A European initiative to unclog pipeline for new medicines.
Nature
; 568(7753): 458, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31015692
7.
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research.
BMC Vet Res
; 16(1): 242, 2020 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32660541
8.
Good Research Practice: Lessons from Animal Care and Use.
Handb Exp Pharmacol
; 257: 367-382, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31541324
9.
Metabolomic biosignature differentiates melancholic depressive patients from healthy controls.
BMC Genomics
; 17: 669, 2016 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27549765
10.
Do wholes become more than the sum of their parts in the rodent (Rattus Norvegicus) visual system? A test case with the configural superiority effect.
Eur J Neurosci
; 44(8): 2593-2599, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471169
11.
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.
J Pharmacol Exp Ther
; 357(2): 394-414, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26989142
12.
Preliminary investigation of 6,7-dihydropyrazolo[1,5-a]pyrazin-4-one derivatives as a novel series of mGlu5 receptor positive allosteric modulators with efficacy in preclinical models of schizophrenia.
Bioorg Med Chem Lett
; 26(2): 429-434, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684851
13.
Further optimization of the mGlu5 PAM clinical candidate VU0409551/JNJ-46778212: Progress and challenges towards a back-up compound.
Bioorg Med Chem Lett
; 25(17): 3515-9, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26183084
14.
Acyl dihydropyrazolo[1,5-a]pyrimidinones as metabotropic glutamate receptor 5 positive allosteric modulators.
Bioorg Med Chem Lett
; 25(22): 5115-20, 2015 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475522
15.
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).
Bioorg Med Chem Lett
; 25(6): 1310-7, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25683622
16.
Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiency.
Bioorg Med Chem Lett
; 24(15): 3641-6, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24961642
17.
The EQIPD quality system - Assessment and certification procedures.
J Neurosci Methods
; 403: 110053, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38163446
18.
Practical solutions for including sex as a biological variable (SABV) in preclinical neuropsychopharmacological research.
J Neurosci Methods
; 401: 110003, 2024 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37918446
19.
Touching on translation.
Cell Tissue Res
; 354(1): 297-308, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23949375
20.
Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions.
Drug Metab Dispos
; 41(12): 2066-75, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24003250