Detalhe da pesquisa
1.
Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons.
J Neurosci
; 39(47): 9294-9305, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591157
2.
Purkinje cells derived from TSC patients display hypoexcitability and synaptic deficits associated with reduced FMRP levels and reversed by rapamycin.
Mol Psychiatry
; 23(11): 2167-2183, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29449635
3.
Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons.
Stem Cells
; 31(8): 1548-62, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23666606
4.
Combining Off-flow, a Nextflow-coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs.
Comput Struct Biotechnol J
; 23: 638-647, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38283851
5.
Non-canonical functions of a mutant TSC2 protein in mitotic division.
PLoS One
; 18(10): e0292086, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37792789
6.
Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts.
Elife
; 102021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34259631
7.
16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro.
Nat Commun
; 12(1): 2897, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006844
8.
Modeling Neurodevelopmental Deficits in Tuberous Sclerosis Complex with Stem Cell Derived Neural Precursors and Neurons.
Adv Neurobiol
; 25: 1-31, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32578142
9.
Strong lymphoid nuclear expression of SOX11 transcription factor defines lymphoblastic neoplasms, mantle cell lymphoma and Burkitt's lymphoma.
Haematologica
; 94(11): 1563-8, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19880779
10.
Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1.
J Neurosci
; 26(20): 5402-10, 2006 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16707792
11.
Crystal structure of the second PDZ domain of SAP97 in complex with a GluR-A C-terminal peptide.
FEBS J
; 273(22): 5219-29, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17069616
12.
Cerebellar Development and Autism Spectrum Disorder in Tuberous Sclerosis Complex.
J Child Neurol
; 30(14): 1954-62, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26303409
13.
Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease.
Cell Stem Cell
; 16(3): 269-74, 2015 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25732245
14.
Advances in stem-cell--generated transplantation therapy for Parkinson's disease.
Expert Opin Biol Ther
; 14(4): 437-53, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24437368
15.
The heteromultimeric debranching enzyme involved in starch synthesis in Arabidopsis requires both isoamylase1 and isoamylase2 subunits for complex stability and activity.
PLoS One
; 8(9): e75223, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24098685
16.
Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
Sci Transl Med
; 4(141): 141ra90, 2012 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22764206
17.
A xeno-free culturing protocol for pluripotent stem cell-derived oligodendrocyte precursor cell production.
Regen Med
; 6(4): 449-60, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21749203
18.
Production and isolation of NG2+ oligodendrocyte precursors from human embryonic stem cells in defined serum-free medium.
Stem Cell Res
; 5(2): 91-103, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20538536
19.
CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells.
Stem Cell Res
; 2(2): 113-24, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19383417