Detalhe da pesquisa
1.
Ageing-associated changes in transcriptional elongation influence longevity.
Nature
; 616(7958): 814-821, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046086
2.
Xrp1 governs the stress response program to spliceosome dysfunction.
Nucleic Acids Res
; 52(5): 2093-2111, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38303573
3.
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity.
Proc Natl Acad Sci U S A
; 116(42): 20817-20819, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570569
4.
A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance.
Mol Syst Biol
; 13(9): 939, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916541
5.
Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila.
PLoS Biol
; 12(4): e1001824, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24690889
6.
Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation.
Nucleic Acids Res
; 42(22): 13920-38, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25428350
7.
FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity.
Front Cell Dev Biol
; 9: 625715, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33634126
8.
Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production.
Aging Cell
; 19(1): e13043, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31721422
9.
Dietary regulation of hypodermal polyploidization in C. elegans.
BMC Dev Biol
; 8: 28, 2008 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18366811
10.
Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila.
Elife
; 62017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28699890
11.
Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice.
Sci Rep
; 6: 30290, 2016 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27452396
12.
Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis.
Cell Rep
; 15(3): 638-650, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068460
13.
Lithium suppresses Aß pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease.
Front Aging Neurosci
; 6: 190, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25126078
14.
Translating translation: regulated protein translation as a biomedical intervention.
Fly (Austin)
; 3(4): 278-80, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19875944
15.
Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.
Nat Neurosci
; 12(9): 1129-35, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19684592