Detalhe da pesquisa
1.
An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice.
Gastroenterology
; 155(6): 1985-1998.e5, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144430
2.
Dynamic heterogeneity of DNA methylation and hydroxymethylation in embryonic stem cell populations captured by single-cell 3D high-content analysis.
Exp Cell Res
; 332(2): 190-201, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25700729
3.
Highly sensitive noninvasive early lung cancer detection using DNA methylation topology in sputum-derived epithelial cells.
JTCVS Open
; 13: 389-410, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37063144
4.
DNA methylation topology differentiates between normal and malignant in cell models, resected human tissues, and exfoliated sputum cells of lung epithelium.
Front Oncol
; 12: 991120, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36387135
5.
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
Exp Cell Res
; 316(19): 3150-60, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20813111
6.
Covisualization of Global DNA Methylation/Hydroxymethylation and Protein Biomarkers for Ultrahigh-Definition Epigenetic Phenotyping of Stem Cells.
Methods Mol Biol
; 2150: 79-92, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768817
7.
Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment.
Cytometry A
; 75(7): 569-83, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19459215
8.
Prostate cancer diagnosis using epigenetic biomarkers, 3D high-content imaging and probabilistic cell-by-cell classifiers.
Oncotarget
; 8(34): 57278-57301, 2017 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28915670
9.
Rapid 3-D delineation of cell nuclei for high-content screening platforms.
Comput Biol Med
; 69: 328-38, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982066
10.
Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas.
Invest Ophthalmol Vis Sci
; 46(10): 3604-15, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16186340
11.
Evaluation of techniques using amplified nucleic acid probes for gene expression profiling.
Biomol Eng
; 20(3): 97-106, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12684071
12.
Covisualization of methylcytosine, global DNA, and protein biomarkers for In Situ 3D DNA methylation phenotyping of stem cells.
Methods Mol Biol
; 1052: 77-88, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23592032
13.
Nuclear DNA methylation and chromatin condensation phenotypes are distinct between normally proliferating/aging, rapidly growing/immortal, and senescent cells.
Oncotarget
; 4(3): 474-93, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23562889
14.
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
BMC Pharmacol Toxicol
; 14: 11, 2013 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23394161
15.
DNA methylation topology: potential of a chromatin landmark for epigenetic drug toxicology.
Epigenomics
; 3(6): 761-70, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22126294
16.
Early in vitro differentiation of mouse definitive endoderm is not correlated with progressive maturation of nuclear DNA methylation patterns.
PLoS One
; 6(7): e21861, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21779341
17.
Topology of genes and nontranscribed sequences in human interphase nuclei.
Exp Cell Res
; 301(2): 266-79, 2004 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15530862