Detalhe da pesquisa
1.
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis.
Bioessays
; : e2400054, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38713169
2.
Stress granule assembly in vivo is deficient in the CNS of mutant TDP-43 ALS mice.
Hum Mol Genet
; 32(2): 319-332, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35994036
3.
Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis.
J Neurochem
; 168(2): 115-127, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38087504
4.
Venous thromboembolism risk in amyotrophic lateral sclerosis: a hospital record-linkage study.
J Neurol Neurosurg Psychiatry
; 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38548323
5.
Advantages of routine next-generation sequencing over standard genetic testing in the amyotrophic lateral sclerosis clinic.
Eur J Neurol
; 30(8): 2240-2249, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37159497
6.
The impact of age on genetic testing decisions in amyotrophic lateral sclerosis.
Brain
; 145(12): 4440-4447, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162820
7.
Is good housekeeping the key to motor neuron survival?
Cell
; 133(4): 572-4, 2008 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18485864
8.
Modeling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis.
Neuroimage
; 251: 118968, 2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143975
9.
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
Hum Mol Genet
; 29(13): 2200-2217, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504093
10.
Higher blood high density lipoprotein and apolipoprotein A1 levels are associated with reduced risk of developing amyotrophic lateral sclerosis.
J Neurol Neurosurg Psychiatry
; 93(1): 75-81, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34518331
11.
Pathological laughter and crying in neurological disorders: recognition and treatment.
Pract Neurol
; 22(6): 486-490, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35907635
12.
Genetic testing in motor neurone disease.
Pract Neurol
; 22(2): 107-116, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027459
13.
Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.
Hum Mol Genet
; 28(21): 3584-3599, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31642482
14.
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Neurobiol Dis
; 144: 105050, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800996
15.
Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource.
Genome Res
; 27(1): 165-173, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003435
16.
CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis.
Clin Proteomics
; 17: 31, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32821252
17.
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Brain
; 142(3): 586-605, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698736
18.
Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations.
Proc Natl Acad Sci U S A
; 114(16): E3324-E3333, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28351971
19.
Primary lateral sclerosis: diagnosis and management.
Pract Neurol
; 20(4): 262-269, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32217663
20.
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
Neurobiol Dis
; 121: 148-162, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30290270