Detalhe da pesquisa
1.
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.
Cell
; 159(2): 402-14, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25303533
2.
Identification of Causal Genetic Drivers of Human Disease through Systems-Level Analysis of Regulatory Networks.
Cell
; 166(4): 1055, 2016 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27518566
3.
ECMarker: interpretable machine learning model identifies gene expression biomarkers predicting clinical outcomes and reveals molecular mechanisms of human disease in early stages.
Bioinformatics
; 37(8): 1115-1124, 2021 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305308
4.
A luminal intermediate cell state maintains long-term prostate homeostasis and contributes to tumorigenesis.
bioRxiv
; 2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36909551
5.
Immune mechanisms shape the clonal landscape during early progression of prostate cancer.
Dev Cell
; 58(12): 1071-1086.e8, 2023 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148881
6.
Role of the p53 family in stabilizing the genome and preventing polyploidization.
Adv Exp Med Biol
; 676: 73-91, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20687470
7.
Mitochondrially targeted p53 has tumor suppressor activities in vivo.
Cancer Res
; 65(21): 9971-81, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16267022
8.
A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue.
Nat Commun
; 8: 14662, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28429718
9.
Cortical hypoplasia and ventriculomegaly of p73-deficient mice: Developmental and adult analysis.
J Comp Neurol
; 522(11): 2663-79, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24500610
10.
While p73 is essential, p63 is completely dispensable for the development of the central nervous system.
Cell Cycle
; 10(4): 680-9, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21293190
11.
Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
Mol Cancer Res
; 9(5): 577-88, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478269
12.
E2F1 plays a direct role in Rb stabilization and p53-independent tumor suppression.
Cell Cycle
; 7(12): 1776-81, 2008 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18583939
13.
p73 suppresses polyploidy and aneuploidy in the absence of functional p53.
Mol Cell
; 27(4): 647-59, 2007 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17707235
14.
p63 and canonical Wnt signaling.
Cell Cycle
; 9(4): 648-9, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20190579
15.
Brdm2 - an aberrant hypomorphic p63 allele.
Cell Death Differ
; 17(1): 184-186, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20161489