RESUMO
Sharing patient information between hospital and pharmacy is an important requirement to ensure safe and effective chemotherapy in outpatients. However, the usefulness of the information feedback from community pharmacies to the hospital has not been clarified. In this study, we analyzed feedback information with the aim of evaluating the usefulness of information feedback from pharmacies through a cooperation system based on information sharing in hospital and pharmacies. The type of information feedback was the most common side effect of supportive therapy, followed by confirmation/ inquiries of treatment contents, abnormality in clinical laboratory test values, etc. In total, 31.0% of the feedbacked information was information not described in the medical record. As a result of feedback of 38.0%, medication therapy was changed. Totally, 73.7% of the information not described in the medical record, but received through feedback, resulted in changes in medication therapy. The information feedback by sharing information on outpatient chemotherapy at pharmacies and hospitals was expected to contribute to patient safety and quality of life during outpatient chemotherapy.
Assuntos
Serviços Comunitários de Farmácia , Farmácias , Hospitais , Humanos , Pacientes Ambulatoriais , Qualidade de Vida , Interface Usuário-ComputadorRESUMO
PURPOSE: To describe the real-world treatment patterns of systemic therapies for biliary tract cancer (BTC) and to examine the frequency and management of biliary infection in Japan. METHODS: Patients diagnosed with BTC and prescribed systemic therapy between January 2011 and September 2020 were retrieved from the Japanese Medical Data Vision database. The look-back period was set to 5 years. Patient characteristics, treatment patterns, and biliary infection-induced treatment interruption were analyzed. RESULTS: The full analysis set comprised 22 742 patients with a mean age of 71.0 years and 61.6% were male. The most common BTC type was extrahepatic cholangiocarcinoma (44.6%). The three most common first-line regimens were S-1 monotherapy (33.0%), gemcitabine+cisplatin (32.5%), and gemcitabine monotherapy (18.7%) over the entire observation period (January 2011-September 2021). Patients who received monotherapies tended to be older. Biliary infection-induced treatment interruption occurred in 29.5% of patients, with a median time to onset of 64.0 (interquartile range 29.0-145.0) days. The median duration of intravenous antibiotics was 12.0 (interquartile range 4.0-92.0) days. CONCLUSIONS: These results demonstrated potential challenges of BTC in Japanese clinical practice particularly use of multiple regimens, commonly monotherapies, which are not recommended as first-line treatment, and the management of biliary infections during systemic therapy.