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2.
Asian Cardiovasc Thorac Ann ; 26(3): 242-244, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29448830

RESUMO

Mucormycosis is an opportunistic fungal infection that can infect different regions of the body. This entity may present in rhinocerebral, pulmonary, cutaneous, and disseminated forms. Although pulmonary mucormycosis is usually seen as an invasive parenchymal consolidation or cavitation, it may rarely present as an endobronchial mass. We describe a case of endobronchial mucormycosis in which the fungal mass was completely removed via rigid bronchoscopy before medical therapy.


Assuntos
Pneumopatias Fúngicas/diagnóstico , Neoplasias Pulmonares/diagnóstico , Mucormicose/diagnóstico , Antifúngicos/administração & dosagem , Biópsia , Broncoscopia , Terapia Combinada , Diagnóstico Diferencial , Feminino , Humanos , Pneumopatias Fúngicas/microbiologia , Pneumopatias Fúngicas/terapia , Pessoa de Meia-Idade , Mucormicose/microbiologia , Mucormicose/terapia , Valor Preditivo dos Testes , Tomografia Computadorizada por Raios X , Resultado do Tratamento
3.
Turk Thorac J ; 18(4): 134-136, 2017 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29404178

RESUMO

Pulmonary alveolar microlithiasis is a rare infiltrative pulmonary disease, in which intraalveolar accumulation of small stones (microliths) consisting of calcium phosphatite occurs. It is an autosomal recessive disorder. The disease occurs as a result of the disruption of type IIb sodium phosphate cotransporter in type II alveolar cells after the mutation of SLC34A2. Majority of patients are diagnosed between age 20 and 40. Here, we present a case of alveolar microlithiasis that was diagnosed with transbronchial biopsy.

4.
Turk J Med Sci ; 46(1): 91-6, 2016 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-27511340

RESUMO

BACKGROUND/AIM: The collection of fluids, blood, pus, or air in the pleural cavity is a pathological condition requiring pleural drainage. A newly designed thorax drainage catheter in the prototype phase was used in this experimental study to test its efficacy. MATERIALS AND METHODS: A hemopneumothorax was first caused by a penetrating injury on the frontal axis of the sixth intercostal space on the right hemithorax with a scalpel on 6 female Sus domesticus swine subjects. After resting for 5 min, a tube or catheter was inserted. The same procedure with a tube thoracostomy or thorax drainage catheter was repeated on the left hemithorax. The time periods were recorded. After all procedures were completed, the thoracic organs were assessed for iatrogenic injuries. RESULTS: In terms of time elapsed for procedure, statistically significant differences between the tube thoracostomy and thorax drainage catheter applications were identified (P < 0.05). Additional iatrogenic injuries were nonexistent for both groups. During the thorax drainage catheter application, a surgical set or the use of sutures was not required. CONCLUSION: This study showed promising results regarding the efficacy of the thorax drainage catheter for convenient use in prehospital and hospital settings by physicians with little experience with tube thoracostomy.


Assuntos
Toracostomia , Toracotomia , Animais , Catéteres , Drenagem , Feminino , Suínos
5.
Ulus Travma Acil Cerrahi Derg ; 21(4): 306-8, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-26374421

RESUMO

Tension gastrothorax is a very rare but potentially fatal clinical condition in which the stomach that herniates through a diaphragmatic defect into the thorax is massively distended by trapped air. It leads to severe symptoms due to the compression of the lung and mediastinum. A 27-year-old female, who had no prior trauma history, applied to the emergency service with the complaint of respiratory disorder, and was consulted by the department of thoracic surgery. Thorax CT revealed presence of gastrothorax in the left hemithorax. Thus, the patient went into cardiopulmonary arrest and was resuscitated. Emergency thoracotomy was performed, abdominal organs were reduced and diaphragmatic defect was repaired. She was discharged on the fifth postoperative day without any complications.


Assuntos
Parada Cardíaca/etiologia , Hérnia Diafragmática Traumática/diagnóstico , Pneumotórax/etiologia , Transtornos Respiratórios/diagnóstico , Adulto , Emergências , Feminino , Hérnia Diafragmática Traumática/complicações , Hérnia Diafragmática Traumática/diagnóstico por imagem , Hérnia Diafragmática Traumática/cirurgia , Humanos , Transtornos Respiratórios/complicações , Transtornos Respiratórios/diagnóstico por imagem , Transtornos Respiratórios/cirurgia , Toracotomia , Tomografia Computadorizada por Raios X
6.
Ulus Travma Acil Cerrahi Derg ; 20(4): 227-30, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25135014

RESUMO

BACKGROUND: This study was planned to analyze the internal and external anatomical findings of cardiac injuries and the presence of accompanying pulmonary injuries in intentionally inflicted thoracic injuries to swine models. METHODS: We inflicted a penetrating heart injury in six suis domesticus female swine models. Two cardiac injuries, one on the left paratracheal of fourth intercostal space (ICS) and the other on the right side were inflicted on each model by the same researcher using a 20-cm long scalpel. All animals were then sacrificed for morphological evaluation. RESULTS: After strikes to the left fourth ICS, external evaluation showed that 50% of the subjects suffered a single laceration and that 33% suffered multiple lacerations. Internal evaluation showed additional intracardiac injuries in all five subjects. However, the subject that suffered a single laceration on the outer surface of the heart had multiple internal injuries while another subject that had multiple outer lacerations had only one intracardiac injury. Only three subjects suffered cardiac injuries and only two out of those three with pulmonary injuries after right fourth intercostal intrusions. CONCLUSION: This experiment has shown that external evaluation of the heart tissue may not alone be sufficient to determine the extent of cardiac injuries and accompanying pulmonary injuries caused by penetrating thoracic injuries.


Assuntos
Traumatismos Cardíacos/fisiopatologia , Lesão Pulmonar/fisiopatologia , Ferimentos Penetrantes/fisiopatologia , Animais , Modelos Animais de Doenças , Feminino , Suínos
7.
Turk J Med Sci ; 44(6): 935-40, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25552144

RESUMO

BACKGROUND/AIM: Penetrating heart injuries result in high mortality. We designed a new catheter to facilitate the treatment of penetrating cardiac injuries and provide more effective initial bleeding control and fluid replacement. MATERIALS AND METHODS: The cardiac injury model was applied to 8 female 1-year-old Sus domesticus pigs. Subjects were grouped according to whether a Foley catheter or a newly designed catheter was placed into the heart through cardiac lacerations. Changes in systolic blood pressures, mortality, and problems encountered during surgery and other intraoperative findings were recorded. RESULTS: There were higher mean blood pressure measurements in the newly designed catheter group during stages IV to VII. All subjects had tamponade and cardiac activity after completion of the repair of all lacerations in the catheter group, whereas in the other group only one subject did. Intraoperative direct fluid infusion to the heart through the catheters in the diastole was performed in all subjects of both groups. However, regurgitation from the cardiac cavity in the systole was seen only in the Foley catheter group. All of the intraoperative complications were seen in the same group.


Assuntos
Oclusão com Balão/instrumentação , Catéteres , Traumatismos Cardíacos/terapia , Animais , Desenho de Equipamento , Feminino , Ventrículos do Coração/lesões , Hemorragia/prevenção & controle , Sus scrofa
8.
BMJ Case Rep ; 20132013 Jun 10.
Artigo em Inglês | MEDLINE | ID: mdl-23761506

RESUMO

Cryptogenic organising pneumonia is not considered in the differential diagnosis of bilateral hilar and mediastinal lymphadenopathy. We submitted a patient presenting with bilateral hilar and mediastinal lymphadenopathy. We suspected diagnosis of sarcoidosis, but the patient was diagnosed as cryptogenic organising pneumonia with the histological result. This is the second case report of cryptogenic organising pneumonia presenting with bilateral hilar and mediastinal lymphadenopathy.


Assuntos
Doenças Linfáticas/diagnóstico , Mediastino/patologia , Pneumonia/diagnóstico , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Doenças Linfáticas/complicações , Doenças Linfáticas/tratamento farmacológico , Doenças Linfáticas/patologia , Pneumonia/complicações , Pneumonia/tratamento farmacológico , Pneumonia/patologia , Prednisona/uso terapêutico
9.
Sultan Qaboos Univ Med J ; 13(1): 165-8, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23573401

RESUMO

Pulmonary embolism due to hydatid disease is an unusual condition resulting from the rupture of a hydatic heart cyst or the opening of liver hydatidosis into the venous circulation. A 78-year old male patient complaining of dyspnea, cough and severe chest pain was admitted to our emergency department. A multidetector computed tomography of the chest revealed the presence of multiple nodules in both lungs especially in left and multiple hypodense filling defect in left main pulmonary artery and its branches. In addition, coronal reformatted multidetector computed tomography images also showed two hypodense cystic parenchymal masses on the left lobe of the liver with a cystic embolus in the right atrium. Pulmonary embolism should be kept in mind in patients who have hepatic hydatidosis if suddenly chest pain and dyspnoea occurs, especially in regions where hydatidosis is endemic.

10.
Balkan Med J ; 30(1): 99-104, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25207078

RESUMO

OBJECTIVE: Methotrexate (MTX) is known to have deleterious side effects on lung tissue. We aimed to investigate the effects of erythropoietin (EPO) and N-acetyl-cysteine (NAC) on MTX-induced lung injury in rats. STUDY DESIGN: Animal experiment. MATERIAL AND METHODS: Twenty-six female Sprague-Dawley rats were divided into 4 groups. Sham group, 0.3 mL saline; MTX group, 5 mg/kg MTX; EPO group, 5mg/kg MTX and 2000 IU/kg EPO; NAC group, 5 mg/kg MTX and 200 mg/kg NAC were administered once daily for 4 consecutive days. Malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT) and inflammation and congestion scores in lung tissues were evaluated. RESULTS: In MTX group MDA were significantly higher, CAT and SOD were significantly lower than in sham, EPO and NAC groups (p<0.005). In EPO group MDA, CAT, and SOD were higher, but not significant than those in group NAC (p>0.005). In group MTX both scores were significantly higher than in sham (p<0.005). The congestion score of group MTX was significantly higher than those of group EPO and NAC (p<0.005). CONCLUSION: EPO and NAC have significant preventive effects on MTX-induced lung injury in rats. Decreased antioxidant capacity and increased MDA level may cause the oxidative damage in MTX group. Also, higher antioxidant capacity and lower MDA level may be a response to oxidative stress in EPO and NAC groups.

11.
BMJ Case Rep ; 20122012 Nov 30.
Artigo em Inglês | MEDLINE | ID: mdl-23203187

RESUMO

Granulomatosis with polyangiitis (GPA) (Wegener's) is a multiorgan system disease of unknown aetiology characterised by granulomatous inflammation, tissue necrosis and vasculitis. The characteristic lung parenchymal lesions of GPA are firm spherical nodules that may cavitate. Pneumothorax (PX) can develop as a quiet rare complication of cavitary nodules. Our case admitted to our clinic with the diagnosis of GPA showing cavitary pulmonary mass. While taking immunosuppressive treatment, spontaneous PX on left lung was developed. A closed chest tube was inserted to the left lung for expansion of PX. Even after 30 days, the left lung did not re-expand and wedge resection with thoracotomy was conducted and the closed chest tube was still in the left lung. On the seventh day, empyema emerged as a complication and, with appropriate treatment, the patient became well. In GPA patients taking immunosuppressive medication, PX is a serious complication and requires aggressive therapy with broad-spectrum antibiotics.


Assuntos
Empiema Pleural/tratamento farmacológico , Granulomatose com Poliangiite/complicações , Pneumopatias/etiologia , Pneumotórax/etiologia , Pseudomonas aeruginosa , Adulto , Antibacterianos/uso terapêutico , Anti-Inflamatórios/uso terapêutico , Cilastatina/uso terapêutico , Combinação Imipenem e Cilastatina , Ciclofosfamida/uso terapêutico , Combinação de Medicamentos , Empiema Pleural/microbiologia , Granulomatose com Poliangiite/tratamento farmacológico , Humanos , Imipenem/uso terapêutico , Imunossupressores/uso terapêutico , Pneumopatias/patologia , Masculino , Pneumotórax/cirurgia , Prednisona/uso terapêutico
15.
Ann Thorac Surg ; 84(6): 2076-9, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18036939

RESUMO

PURPOSE: In this clinical study we investigated the use and results of the LigaSure Vessel Sealing Sytem (LVSS) (Valleylab, Boulder, CO) compared with conventional surgery in esophageal cancer resection. DESCRIPTION: The LVSS (Valleylab) is a device with a hemostatic design frequently used in abdominal surgery. Sixty patients (n = 30 in each group) with esophageal cancer from a single center were evaluated to undergo esophagectomy using either the LVSS or conventional clamping methods. The main outcome measures (ie, operating time, intraoperative blood loss, and postoperative course) were then compared. EVALUATION: In resections performed using the LVSS, operation duration (307 +/- 35 minutes vs 260 +/- 35 minutes; p = 0.000), intraoperative blood loss (average 533 +/- 211 mL vs 390 +/- 256 mL; p = 0.022), and postoperative drainage volumes (abdomen, 70 +/- 86 mL vs 40 +/- 61 mL; p = 0.122; thorax, 690 +/- 646 mL vs 540 +/- 359 mL; p = 0.271) all decreased. CONCLUSIONS: The LVSS is easy to use and a reliable method in esophageal cancer surgery. Compared with conventional hemostatic techniques a reduction in intraoperative and postoperative blood loss, and a shortening of operation duration were determined. We believe that the use of the LVSS in esophageal surgery will become even more widespread in the future.


Assuntos
Neoplasias Esofágicas/cirurgia , Esofagectomia/instrumentação , Hemostasia Cirúrgica/instrumentação , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Estudos Prospectivos
16.
Asian Cardiovasc Thorac Ann ; 14(3): 244-6, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16714705

RESUMO

An 18-month-old girl presented with high fever and vomiting. Pneumothorax and a cystic formation in the right hemithorax were found on a chest radiograph. The cyst measuring 10 x 10 x 8 cm was resected by a simple wedge resection. Histology revealed a complicated bronchogenic cyst with abscess formation.


Assuntos
Cisto Broncogênico/diagnóstico por imagem , Cisto Broncogênico/cirurgia , Pneumotórax/diagnóstico por imagem , Pneumotórax/cirurgia , Diagnóstico Diferencial , Feminino , Humanos , Lactente , Tomografia Computadorizada por Raios X
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