Detalhe da pesquisa
1.
GLI1 interaction with p300 modulates SDF1 expression in cancer-associated fibroblasts to promote pancreatic cancer cells migration.
Biochem J
; 480(3): 225-241, 2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734208
2.
The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex.
J Biol Chem
; 295(9): 2698-2712, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31988246
3.
GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.
Biochem J
; 477(17): 3131-3145, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32766732
4.
Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer.
Pancreatology
; 20(1): 101-109, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31787526
5.
Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming.
Gut
; 68(7): 1271-1286, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30337373
6.
Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.
J Biol Chem
; 291(49): 25749-25760, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760825
7.
Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid.
J Biol Chem
; 291(4): 1933-1947, 2016 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26601952
8.
Modulation of the IL-6 Receptor α Underlies GLI2-Mediated Regulation of Ig Secretion in Waldenström Macroglobulinemia Cells.
J Immunol
; 195(6): 2908-16, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238488
9.
Targeting tumour microenvironment, a FAKtual challenge in pancreatic cancer.
Gut
; 69(1): 1-2, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31582402
10.
The transcription factor GLI1 interacts with SMAD proteins to modulate transforming growth factor ß-induced gene expression in a p300/CREB-binding protein-associated factor (PCAF)-dependent manner.
J Biol Chem
; 289(22): 15495-506, 2014 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24739390
11.
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression.
Cancer Discov
; 14(2): 348-361, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37966260
12.
PFKFB3 controls acinar IP3R-mediated Ca2+ overload to regulate acute pancreatitis severity.
JCI Insight
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38781030
13.
Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.
JCI Insight
; 7(22)2022 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256477
14.
Nuclear Dynamics and Chromatin Structure: Implications for Pancreatic Cancer.
Cells
; 10(10)2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34685604
15.
Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion.
Mol Ther Oncolytics
; 20: 659-668, 2021 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33816784
16.
LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.
PLoS One
; 16(5): e0250518, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34033669
17.
RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis.
Nat Commun
; 12(1): 2901, 2021 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34006870
18.
Impaired Hedgehog-Gli1 Pathway Activity Underlies the Vascular Phenotype of Polycystic Kidney Disease.
Hypertension
; 76(6): 1889-1897, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33012205
19.
Induction of Lysosome-associated Protein Transmembrane 4 Beta via Sulfatase 2 Enhances Autophagic Flux in Liver Cancer Cells.
Hepatol Commun
; 3(11): 1520-1543, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701075
20.
Transcriptional Induction of Periostin by a Sulfatase 2-TGFß1-SMAD Signaling Axis Mediates Tumor Angiogenesis in Hepatocellular Carcinoma.
Cancer Res
; 77(3): 632-645, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27872089