Detalhe da pesquisa
1.
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
PLoS Pathog
; 14(12): e1007439, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30576397
2.
Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis.
ACS Pharmacol Transl Sci
; 7(5): 1302-1309, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751629
3.
Identification and Characterization of a Small Molecule Bcl-2 Functional Converter.
Cancer Res Commun
; 4(3): 634-644, 2024 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329389
4.
Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans.
Antimicrob Agents Chemother
; 57(3): 1136-43, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23254433
5.
A novel inhibitor of dengue virus replication that targets the capsid protein.
Antimicrob Agents Chemother
; 57(1): 15-25, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23070172
6.
Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase.
Antimicrob Agents Chemother
; 57(4): 1902-12, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403421
7.
Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis.
Blood Adv
; 7(19): 5835-5842, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37552106
8.
Pharmacokinetic comparison of a single oral dose of polymorph form i versus form V capsules of the antiorthopoxvirus compound ST-246 in human volunteers.
Antimicrob Agents Chemother
; 56(7): 3582-6, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22526314
9.
Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers.
Antimicrob Agents Chemother
; 56(9): 4900-5, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22777041
10.
SAR analysis of a series of acylthiourea derivatives possessing broad-spectrum antiviral activity.
Bioorg Med Chem Lett
; 22(13): 4263-72, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22664128
11.
Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects.
Antimicrob Agents Chemother
; 54(6): 2560-6, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20385870
12.
Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis.
Blood Adv
; 4(22): 5825-5835, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33232476
13.
ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.
Antimicrob Agents Chemother
; 53(5): 1817-22, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19223621
14.
Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor.
Antimicrob Agents Chemother
; 52(5): 1721-7, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316519
15.
Pharmacokinetics and interspecies allometric scaling of ST-246, an oral antiviral therapeutic for treatment of orthopoxvirus infection.
PLoS One
; 8(4): e61514, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637845
16.
Comparison of the safety and pharmacokinetics of ST-246® after i.v. infusion or oral administration in mice, rabbits and monkeys.
PLoS One
; 6(8): e23237, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21858040
17.
Development of ST-246® for Treatment of Poxvirus Infections.
Viruses
; 2(11): 2409-2435, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21994624
18.
Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.
Vaccine
; 26(7): 933-46, 2008 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18226434