Detalhe da pesquisa
1.
PAR2 activation in the dura causes acute behavioral responses and priming to glyceryl trinitrate in a mouse migraine model.
J Headache Pain
; 24(1): 42, 2023 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37072694
2.
Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression.
Biochem Biophys Res Commun
; 591: 13-19, 2022 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990903
3.
Multivalent activation of GLP-1 and sulfonylurea receptors modulates ß-cell second-messenger signaling and insulin secretion.
Am J Physiol Cell Physiol
; 316(1): C48-C56, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30404557
4.
The lipidated connexin mimetic peptide SRPTEKT-Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform.
Am J Physiol Cell Physiol
; 317(4): C825-C842, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31365296
5.
Protease activated receptor 2 (PAR2) activation causes migraine-like pain behaviors in mice.
Cephalalgia
; 39(1): 111-122, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29848111
6.
The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.
J Neurosci
; 37(31): 7481-7499, 2017 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28674170
7.
Lipidated connexin mimetic peptides potently inhibit gap junction-mediated Ca2+-wave propagation.
Am J Physiol Cell Physiol
; 315(2): C141-C154, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29631365
8.
Delta-Opioid Receptor (δOR) Targeted Near-Infrared Fluorescent Agent for Imaging of Lung Cancer: Synthesis and Evaluation In Vitro and In Vivo.
Bioconjug Chem
; 27(2): 427-38, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26488422
9.
Tumor Targeting and Pharmacokinetics of a Near-Infrared Fluorescent-Labeled δ-Opioid Receptor Antagonist Agent, Dmt-Tic-Cy5.
Mol Pharm
; 13(2): 534-44, 2016 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26713599
10.
Heterobivalent ligands target cell-surface receptor combinations in vivo.
Proc Natl Acad Sci U S A
; 109(52): 21295-300, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23236171
11.
A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance.
Am J Physiol Cell Physiol
; 307(8): C718-26, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25143347
12.
Hetero-bivalent GLP-1/glibenclamide for targeting pancreatic ß-cells.
Chembiochem
; 15(1): 135-45, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24259278
13.
Spectrophotometric determination and removal of unchelated europium ions from solutions containing Eu-diethylenetriaminepentaacetic acid chelate-peptide conjugates.
Anal Biochem
; 464: 24-9, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25058927
14.
Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering.
FASEB J
; 27(4): 1498-510, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23292071
15.
In vivo and in silico pharmacokinetics and biodistribution of a melanocortin receptor 1 targeted agent in preclinical models of melanoma.
Mol Pharm
; 10(8): 3175-85, 2013 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23763620
16.
Synthesis and characterization of time-resolved fluorescence probes for evaluation of competitive binding to melanocortin receptors.
Bioorg Med Chem
; 21(17): 5029-38, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23890524
17.
Protease-Activated Receptor 2 (PAR2) Expressed in Sensory Neurons Contributes to Signs of Pain and Neuropathy in Paclitaxel Treated Mice.
J Pain
; 24(11): 1980-1993, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315729
18.
C781, a ß-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice.
J Pain
; 24(4): 605-616, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417966
19.
ß-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation.
Br J Pharmacol
; 180(5): 667-680, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35735078
20.
The protease-activated receptor-2-specific agonists 2-aminothiazol-4-yl-LIGRL-NH2 and 6-aminonicotinyl-LIGRL-NH2 stimulate multiple signaling pathways to induce physiological responses in vitro and in vivo.
J Biol Chem
; 286(21): 19076-88, 2011 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-21467041