Pesquisa | Portal de Pesquisa da BVS

1.

De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.

Chen, Zhen; Shiozaki, Momoko; Haas, Kelsey M; Skinner, Will M; Zhao, Shumei; Guo, Caiying; Polacco, Benjamin J; Yu, Zhiheng; Krogan, Nevan J; Lishko, Polina V; Kaake, Robyn M; Vale, Ronald D; Agard, David A.

Cell ; 186(23): 5041-5053.e19, 2023 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-37865089

2.

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

Sibener, Leah V; Fernandes, Ricardo A; Kolawole, Elizabeth M; Carbone, Catherine B; Liu, Fan; McAffee, Darren; Birnbaum, Michael E; Yang, Xinbo; Su, Laura F; Yu, Wong; Dong, Shen; Gee, Marvin H; Jude, Kevin M; Davis, Mark M; Groves, Jay T; Goddard, William A; Heath, James R; Evavold, Brian D; Vale, Ronald D; Garcia, K Christopher.

Cell ; 174(3): 672-687.e27, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-30053426

3.

A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination.

Taylor, Marcus J; Husain, Kabir; Gartner, Zev J; Mayor, Satyajit; Vale, Ronald D.

Cell ; 169(1): 108-119.e20, 2017 03 23.

Artigo em Inglês | MEDLINE | ID: mdl-28340336

4.

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.

Ekiert, Damian C; Bhabha, Gira; Isom, Georgia L; Greenan, Garrett; Ovchinnikov, Sergey; Henderson, Ian R; Cox, Jeffery S; Vale, Ronald D.

Cell ; 169(2): 273-285.e17, 2017 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-28388411

5.

Dynamics of Translation of Single mRNA Molecules In Vivo.

Yan, Xiaowei; Hoek, Tim A; Vale, Ronald D; Tanenbaum, Marvin E.

Cell ; 165(4): 976-89, 2016 May 05.

Artigo em Inglês | MEDLINE | ID: mdl-27153498

6.

The cytoplasmic dynein transport machinery and its many cargoes.

Reck-Peterson, Samara L; Redwine, William B; Vale, Ronald D; Carter, Andrew P.

Nat Rev Mol Cell Biol ; 19(6): 382-398, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29662141

7.

Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes.

Reck-Peterson, Samara L; Redwine, William B; Vale, Ronald D; Carter, Andrew P.

Nat Rev Mol Cell Biol ; 19(7): 479, 2018 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-29740130

8.

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.

Morrissey, Meghan A; Kern, Nadja; Vale, Ronald D.

Immunity ; 53(2): 290-302.e6, 2020 08 18.

Artigo em Inglês | MEDLINE | ID: mdl-32768386

9.

Keep Your Eyes on the Prize.

Vale, Ronald D.

Cell ; 177(3): 506-509, 2019 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-30952445

10.

A protein-tagging system for signal amplification in gene expression and fluorescence imaging.

Tanenbaum, Marvin E; Gilbert, Luke A; Qi, Lei S; Weissman, Jonathan S; Vale, Ronald D.

Cell ; 159(3): 635-46, 2014 Oct 23.

Artigo em Inglês | MEDLINE | ID: mdl-25307933

11.

Allosteric communication in the dynein motor domain.

Bhabha, Gira; Cheng, Hui-Chun; Zhang, Nan; Moeller, Arne; Liao, Maofu; Speir, Jeffrey A; Cheng, Yifan; Vale, Ronald D.

Cell ; 159(4): 857-68, 2014 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-25417161

12.

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

Petry, Sabine; Groen, Aaron C; Ishihara, Keisuke; Mitchison, Timothy J; Vale, Ronald D.

Cell ; 152(4): 768-77, 2013 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-23415226

13.

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.

Morrissey, Meghan A; Kern, Nadja; Vale, Ronald D.

Immunity ; 56(9): 2172, 2023 Sep 12.

Artigo em Inglês | MEDLINE | ID: mdl-37703830

14.

Bridging gaps in traditional research training with iBiology Courses.

Schnoes, Alexandra M; Green, Noah H; Nguyen, Thi A; Vale, Ronald D; Goodwin, Sarah S; Behrman, Shannon L.

PLoS Biol ; 22(1): e3002458, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38206957

15.

Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters.

Laan, Liedewij; Pavin, Nenad; Husson, Julien; Romet-Lemonne, Guillaume; van Duijn, Martijn; López, Magdalena Preciado; Vale, Ronald D; Jülicher, Frank; Reck-Peterson, Samara L; Dogterom, Marileen.

Cell ; 148(3): 502-14, 2012 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-22304918

16.

Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs.

Das, Michael R; Chang, Yeonji; Anderson, Rachel; Saunders, Reuben A; Zhang, Nan; Tomberlin, Colson P; Vale, Ronald D; Jain, Ankur.

Proc Natl Acad Sci U S A ; 120(3): e2215071120, 2023 01 17.

Artigo em Inglês | MEDLINE | ID: mdl-36623192

17.

Patronin regulates the microtubule network by protecting microtubule minus ends.

Goodwin, Sarah S; Vale, Ronald D.

Cell ; 143(2): 263-74, 2010 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-20946984

18.

Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR).

Dong, Rui; Libby, Kendra A; Blaeschke, Franziska; Fuchs, Walker; Marson, Alexander; Vale, Ronald D; Su, Xiaolei.

EMBO J ; 39(16): e104730, 2020 08 17.

Artigo em Inglês | MEDLINE | ID: mdl-32643825

19.

Three-color single-molecule imaging reveals conformational dynamics of dynein undergoing motility.

Niekamp, Stefan; Stuurman, Nico; Zhang, Nan; Vale, Ronald D.

Proc Natl Acad Sci U S A ; 118(31)2021 08 03.

Artigo em Inglês | MEDLINE | ID: mdl-34326255

20.

DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation.

Dong, Rui; Aksel, Tural; Chan, Waipan; Germain, Ronald N; Vale, Ronald D; Douglas, Shawn M.

Proc Natl Acad Sci U S A ; 118(40)2021 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-34588308

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De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.

A DNA-Based T Cell Receptor Reveals a Role for Receptor Clustering in Ligand Discrimination.

Architectures of Lipid Transport Systems for the Bacterial Outer Membrane.

Dynamics of Translation of Single mRNA Molecules In Vivo.

The cytoplasmic dynein transport machinery and its many cargoes.

Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes.

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.

Keep Your Eyes on the Prize.

A protein-tagging system for signal amplification in gene expression and fluorescence imaging.

Allosteric communication in the dynein motor domain.

Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.

CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis.

Bridging gaps in traditional research training with iBiology Courses.

Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters.

Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs.

Patronin regulates the microtubule network by protecting microtubule minus ends.

Rewired signaling network in T cells expressing the chimeric antigen receptor (CAR).

Three-color single-molecule imaging reveals conformational dynamics of dynein undergoing motility.

DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation.