Detalhe da pesquisa
1.
Polyamines in Parkinson's Disease: Balancing Between Neurotoxicity and Neuroprotection.
Annu Rev Biochem
; 92: 435-464, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37018845
2.
ATP13A2 deficiency disrupts lysosomal polyamine export.
Nature
; 578(7795): 419-424, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31996848
3.
The lysosome as a master regulator of iron metabolism.
Trends Biochem Sci
; 46(12): 960-975, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34384657
4.
BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.
EMBO J
; 40(10): e106214, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932034
5.
Upregulation of the secretory pathway Ca2+/Mn2+-ATPase isoform 1 in LPS-stimulated microglia and its involvement in Mn2+-induced Golgi fragmentation.
Glia
; 72(6): 1201-1214, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38482950
6.
Structures of the heart specific SERCA2a Ca2+-ATPase.
EMBO J
; 38(5)2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30777856
7.
ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress.
Proc Natl Acad Sci U S A
; 117(49): 31198-31207, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229544
8.
Identification and Characterization of p300-Mediated Lysine Residues in Cardiac SERCA2a.
Int J Mol Sci
; 24(4)2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834924
9.
ATP13A3 is a major component of the enigmatic mammalian polyamine transport system.
J Biol Chem
; 296: 100182, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33310703
10.
CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2.
Hum Mol Genet
; 29(7): 1096-1106, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32068847
11.
The endoplasmic reticulum Ca2+ -ATPase SERCA2b is upregulated in activated microglia and its inhibition causes opposite effects on migration and phagocytosis.
Glia
; 69(4): 842-857, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105046
12.
Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.
Circ Res
; 124(9): e63-e80, 2019 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30786847
13.
ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization.
Int J Mol Sci
; 22(5)2021 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33799982
14.
An N-terminal Ca2+-binding motif regulates the secretory pathway Ca2+/Mn2+-transport ATPase SPCA1.
J Biol Chem
; 294(19): 7878-7891, 2019 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30923126
15.
Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export.
Acta Neuropathol
; 139(6): 1001-1024, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32172343
16.
Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease.
Biochim Biophys Acta Mol Cell Res
; 1865(6): 855-862, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29555205
17.
A Darier disease mutation relieves kinetic constraints imposed by the tail of sarco(endo)plasmic reticulum Ca2+-ATPase 2b.
J Biol Chem
; 293(11): 3880-3889, 2018 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363575
18.
Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).
J Biol Chem
; 292(17): 6938-6951, 2017 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28264934
19.
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78).
Brain
; 140(2): 287-305, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28137957
20.
A lipid switch unlocks Parkinson's disease-associated ATP13A2.
Proc Natl Acad Sci U S A
; 112(29): 9040-5, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26134396