Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros

Base de dados
País/Região como assunto
Ano de publicação
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
Epidemiol Infect ; 141(7): 1481-7, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23414617

RESUMO

A cross-sectional study was conducted from 10 January to 9 April 2012, to determine the seroprevalence of tuberculosis (TB) of all captive Asian elephants and their handlers in six locations in Peninsular Malaysia. In addition, trunk-wash samples were examined for tubercle bacillus by culture and polymerase chain reaction (PCR). For 63 elephants and 149 elephant handlers, TB seroprevalence was estimated at 20.4% and 24.8%, respectively. From 151 trunkwash samples, 24 acid-fast isolates were obtained, 23 of which were identified by hsp65-based sequencing as non-tuberculous mycobacteria. The Mycobacterium tuberculosis-specific PCR was positive in the trunk-wash samples from three elephants which were also seropositive. Conversely, the trunk wash from seven seropositive elephants were PCR negative. Hence, there was evidence of active and latent TB in the elephants and the high seroprevalence in the elephants and their handlers suggests frequent, close contact, two-way transmission between animals and humans within confined workplaces.


Assuntos
Animais de Zoológico , Elefantes , Tuberculose/veterinária , Zoonoses/epidemiologia , Animais , Antígenos de Bactérias/sangue , Biomarcadores/sangue , Estudos Transversais , DNA Bacteriano/análise , Humanos , Testes de Liberação de Interferon-gama , Malásia/epidemiologia , Mycobacterium tuberculosis/genética , Mycobacterium tuberculosis/imunologia , Mycobacterium tuberculosis/isolamento & purificação , Reação em Cadeia da Polimerase , Prevalência , Risco , Estudos Soroepidemiológicos , Tuberculose/diagnóstico , Tuberculose/epidemiologia , Tuberculose/transmissão , Zoonoses/transmissão
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA