Detalhe da pesquisa
1.
YbiB: a novel interactor of the GTPase ObgE.
Nucleic Acids Res
; 51(7): 3420-3435, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36864742
2.
Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217606
3.
Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.
Mol Cell
; 59(1): 9-21, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26051177
4.
Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
Angew Chem Int Ed Engl
; 62(24): e202219095, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37067463
5.
Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies.
Biochem J
; 477(7): 1203-1218, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32167135
6.
Structure-Activity Relationship (SAR) Study of Spautin-1 to Entail the Discovery of Novel NEK4 Inhibitors.
Int J Mol Sci
; 22(2)2021 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435251
7.
Biochemical determinants of ObgE-mediated persistence.
Mol Microbiol
; 112(5): 1593-1608, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31498933
8.
Structural and biochemical analysis of the dual-specificity Trm10 enzyme from Thermococcus kodakaraensis prompts reconsideration of its catalytic mechanism.
RNA
; 24(8): 1080-1092, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29848639
9.
TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.
Brain
; 142(8): 2319-2335, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31257402
10.
Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein.
Biochem J
; 476(1): 51-66, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30538153
11.
Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proc Natl Acad Sci U S A
; 113(30): E4357-66, 2016 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27357661
12.
Roco Proteins: GTPases with a Baroque Structure and Mechanism.
Int J Mol Sci
; 20(1)2019 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30609797
13.
GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE.
Int J Mol Sci
; 21(1)2019 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31861427
14.
Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.
J Biol Chem
; 292(14): 5871-5883, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28223358
15.
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
J Biol Chem
; 292(32): 13097-13110, 2017 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28620052
16.
Biochemical and kinetic properties of the complex Roco G-protein cycle.
Biol Chem
; 399(12): 1447-1456, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067506
17.
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.
Nucleic Acids Res
; 44(2): 940-53, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673726
18.
Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF.
J Biol Chem
; 291(21): 10950-60, 2016 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026704
19.
Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.
RNA
; 20(8): 1257-71, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24951554
20.
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction.
Biopolymers
; 105(8): 568-79, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26832457