Detalhe da pesquisa
1.
Caged Luciferase Inhibitor-Based Bioluminescence Switching Strategy Enables Efficient Detection of Serum APN Activity and the Identification of Its Roles in Metastasis of Non-Small Cell Lung Cancer.
Chemistry
; 29(51): e202300655, 2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37227809
2.
Raloxifene alleviates amyloid-ß-induced cytotoxicity in HT22 neuronal cells via inhibiting oligomeric and fibrillar species formation.
J Biochem Mol Toxicol
; 33(11): e22395, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31583774
3.
Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation.
Nat Commun
; 14(1): 6132, 2023 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783727
4.
Identification of 2-Benzylidene-tetralone Derivatives as Highly Potent and Reversible Firefly Luciferase Inhibitors.
ACS Med Chem Lett
; 13(2): 304-311, 2022 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35178187
5.
Blockade of USP14 potentiates type I interferon signaling and radiation-induced antitumor immunity via preventing IRF3 deubiquitination.
Cell Oncol (Dordr)
; 45(6): 1347-1361, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36205846
6.
Degradation of intracellular TGF-ß1 by PROTACs efficiently reverses M2 macrophage induced malignant pathological events.
Chem Commun (Camb)
; 56(19): 2881-2884, 2020 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037404
7.
Dissociation of haemolytic and oligomer-preventing activities of gramicidin S derivatives targeting the amyloid-ß N-terminus.
Chem Commun (Camb)
; 53(100): 13340-13343, 2017 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188836
8.
Synthesis and evaluation of anticancer activity of BOC26P, an ortho-aryl chalcone sodium phosphate as water-soluble prodrugs in vitro and in vivo.
Biomed Pharmacother
; 96: 551-562, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29032339
9.
Stabilizing amyloid-ß peptide by the N-terminus capture is capable of preventing and eliminating amyloid-ß oligomers.
Chem Commun (Camb)
; 53(54): 7673-7676, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28644501
10.
Stabilizing the monomeric amyloid-ß peptide by tyrocidine A prevents and reverses amyloidogenesis without the accumulation of oligomers.
Chem Commun (Camb)
; 53(27): 3886-3889, 2017 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28317984
11.
Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase.
Biochem Pharmacol
; 137: 29-50, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28476333