Detalhe da pesquisa
1.
Pharmacological Characterization of YM543, a Newly Synthesized, Orally Active SGLT2 Selective Inhibitor.
Endocr Res
; 38(3): 168-183, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23374077
2.
Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin-nicotinamide-induced mildly diabetic mice.
J Pharmacol Sci
; 120(1): 36-44, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22971845
3.
Identification of functional clock-controlled elements involved in differential timing of Per1 and Per2 transcription.
Nucleic Acids Res
; 38(22): 7964-73, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693532
4.
Preclinical Characterization of ASP2713, a Novel Igß and FcγRIIB Cross-Linking Antibody, for Prediction of Human Pharmacokinetics and Clinically Effective Dose.
J Pharm Sci
; 111(9): 2630-2638, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35700799
5.
Regular feeding plays an important role in cholesterol homeostasis through the liver circadian clock.
Circ Res
; 105(6): 545-8, 2009 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19661461
6.
Discovery of a novel Igß and FcγRIIB cross-linking antibody, ASP2713, and its potential application in the treatment of systemic lupus erythematosus.
Int Immunopharmacol
; 101(Pt B): 108343, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34781122
7.
Effects of sodium-glucose cotransporter 2 selective inhibitor ipragliflozin on hyperglycaemia, oxidative stress, inflammation and liver injury in streptozotocin-induced type 1 diabetic rats.
J Pharm Pharmacol
; 66(7): 975-87, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24533859
8.
Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice.
Eur J Pharmacol
; 715(1-3): 246-55, 2013 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23707905
9.
Pharmacological profile of ipragliflozin (ASP1941), a novel selective SGLT2 inhibitor, in vitro and in vivo.
Naunyn Schmiedebergs Arch Pharmacol
; 385(4): 423-36, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22139434
10.
Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock.
Sci Rep
; 2: 439, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22666542
11.
Cellular DBP and E4BP4 proteins are critical for determining the period length of the circadian oscillator.
FEBS Lett
; 585(14): 2217-22, 2011 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21635892