1.
J Org Chem
; 88(1): 647-652, 2023 Jan 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36480338
RESUMO
A visible-light-induced tandem radical brominative addition/spiro-cyclization/1,2-ester migration of activated alkynes with CBr4 is developed. This protocol features good functional group tolerance, operational simplicity, and mild reaction conditions without the use of catalysts and external additives, providing easy access to valuable 3-bromocoumarins in generally high yields.