Detalhe da pesquisa
1.
Dual-targeted hit identification using pharmacophore screening.
J Comput Aided Mol Des
; 33(11): 955-964, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31691918
2.
LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.
Biochim Biophys Acta Mol Cell Res
; 1864(12): 2356-2368, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888991
3.
Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors.
Mol Divers
; 22(4): 991-998, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845490
4.
Production of recombinant human apoptosis signal-regulating kinase 1 (ASK1) in Escherichia coli.
Protein Expr Purif
; 126: 89-92, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27245507
5.
Discovery of potent anti-tuberculosis agents targeting leucyl-tRNA synthetase.
Bioorg Med Chem
; 24(5): 1023-31, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26822568
6.
Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2.
J Enzyme Inhib Med Chem
; 31(sup4): 160-169, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27590574
7.
Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one.
J Enzyme Inhib Med Chem
; 31(sup2): 201-207, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27241561
8.
Trimethine cyanine dyes as fluorescent probes for amyloid fibrils: The effect of N,N'-substituents.
Anal Biochem
; 484: 9-17, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25963892
9.
Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one.
Bioorg Med Chem
; 23(10): 2489-97, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25882527
10.
ASK1 pharmacophore model derived from diverse classes of inhibitors.
Bioorg Med Chem Lett
; 24(18): 4418-4423, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172422
11.
Study of anti-fibrillogenic activity of iron(II) clathrochelates.
Bioorg Med Chem
; 22(6): 1883-8, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24565971
12.
Design, synthesis and evaluation of 2-phenylisothiazolidin-3-one-1,1-dioxides as a new class of human protein kinase CK2 inhibitors.
J Enzyme Inhib Med Chem
; 29(3): 338-43, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23578312
13.
Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors.
J Enzyme Inhib Med Chem
; 29(5): 639-46, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24090425
14.
Identification of novel PARP-1 inhibitors by structure-based virtual screening.
Bioorg Med Chem Lett
; 23(21): 5790-4, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24074844
15.
Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family.
Bioorg Med Chem
; 21(21): 6681-9, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24011954
16.
Interaction of the iron(II) cage complexes with proteins: protein fluorescence quenching study.
J Fluoresc
; 23(5): 889-95, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23553641
17.
Probing interactions of aminoacyl-adenylate with Mycobacterium tuberculosis methionyl-tRNA synthetase through in silico site-directed mutagenesis and free energy calculation.
J Biomol Struct Dyn
; 41(13): 6450-6458, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-35930324
18.
Pharmacophore modeling, docking and molecular dynamics simulation for identification of novel human protein kinase C beta (PKCß) inhibitors.
Struct Chem
; 34(3): 1157-1171, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36248344
19.
Identification of dual-targeted Mycobacterium tuberculosis aminoacyl-tRNA synthetase inhibitors using machine learning.
Future Med Chem
; 14(17): 1223-1237, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35876255
20.
Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.
J Antibiot (Tokyo)
; 75(6): 321-332, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440771