Detalhe da pesquisa
1.
Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.
Proc Natl Acad Sci U S A
; 106(40): 17111-6, 2009 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19805189
2.
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors.
Mutat Res
; 714(1-2): 1-10, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21376736
3.
Generation of mice with a conditional allele for transforming growth factor beta 1 gene.
Genesis
; 47(6): 423-31, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19415629
4.
The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model.
Mutat Res
; 616(1-2): 201-9, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17174984
5.
Expression and loss of alleles in cultured mouse embryonic fibroblasts and stem cells carrying allelic fluorescent protein genes.
BMC Mol Biol
; 7: 36, 2006 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17042952
6.
Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer.
Oncotarget
; 7(15): 20425-39, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26967250
7.
Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice.
Oncogene
; 21(18): 2840-5, 2002 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-11973643
8.
A human cancer-predisposing polymorphism in Cdc25A is embryonic lethal in the mouse and promotes ASK-1 mediated apoptosis.
Cell Div
; 6(1): 4, 2011 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310058
9.
Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.
Cancer Lett
; 296(2): 186-93, 2010 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20434834
10.
Role of Transforming Growth Factor 1 in Lymphocyte Development and Death.
ScientificWorldJournal
; 1: 146, 2001.
Artigo
em Inglês
| MEDLINE | ID: mdl-30147623
11.
Gene targeted ablation of high molecular weight fibroblast growth factor-2.
Dev Dyn
; 238(2): 351-7, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19105223
12.
TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes.
J Immunol
; 170(7): 3645-52, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12646629
13.
TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes.
J Immunol
; 170(9): 4612-22, 2003 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12707339