Detalhe da pesquisa
1.
Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media.
Appl Microbiol Biotechnol
; 107(9): 2855-2870, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36947192
2.
ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models.
Int J Mol Sci
; 22(1)2020 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33383646
3.
NG2 Proteoglycan-Dependent Contributions of Pericytes and Macrophages to Brain Tumor Vascularization and Progression.
Microcirculation
; 23(2): 122-33, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26465118
4.
NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function.
Angiogenesis
; 17(1): 61-76, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23925489
5.
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production.
ACS Synth Biol
; 13(2): 634-647, 2024 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38240694
6.
Collagen VI ablation retards brain tumor progression due to deficits in assembly of the vascular basal lamina.
Am J Pathol
; 180(3): 1145-1158, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22200614
7.
Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development.
Mol Cancer Ther
; 22(1): 3-11, 2023 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36223541
8.
Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan.
Breast Cancer Res
; 14(2): R67, 2012 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22531600
9.
Grabody B, an IGF1 receptor-based shuttle, mediates efficient delivery of biologics across the blood-brain barrier.
Cell Rep Methods
; 2(11): 100338, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36452865
10.
Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse.
Dev Biol
; 344(2): 1035-46, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20599895
11.
Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vessels.
Am J Pathol
; 176(4): 1927-40, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20185574
12.
N-terminal selective conjugation method widens the therapeutic window of antibody-drug conjugates by improving tolerability and stability.
MAbs
; 13(1): 1914885, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33904380
13.
Synergistic antitumor activity of a DLL4/VEGF bispecific therapeutic antibody in combination with irinotecan in gastric cancer.
BMB Rep
; 53(10): 533-538, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32580836
14.
Correlative dynamic contrast MRI and microscopic assessments of tumor vascularity in RIP-Tag2 transgenic mice.
Magn Reson Med
; 62(3): 616-25, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19526501
15.
High delta-like ligand 4 expression correlates with a poor clinical outcome in gastric cancer.
J Cancer
; 10(14): 3172-3178, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31289587
16.
Localization of VEGF to Vascular ECM Is an Important Aspect of Tumor Angiogenesis.
Cancers (Basel)
; 9(8)2017 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28788063
17.
Simultaneous blockade of VEGF and Dll4 by HD105, a bispecific antibody, inhibits tumor progression and angiogenesis.
MAbs
; 8(5): 892-904, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27049350
18.
Development, validation, and application of ELISA for detection of anti-HD105 antibodies in pre-clinical safety evaluation using monkeys.
J Pharm Biomed Anal
; 131: 309-315, 2016 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27619177
19.
Development of antibody-based c-Met inhibitors for targeted cancer therapy.
Immunotargets Ther
; 4: 35-44, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27471710
20.
NG2 proteoglycan-dependent recruitment of tumor macrophages promotes pericyte-endothelial cell interactions required for brain tumor vascularization.
Oncoimmunology
; 4(4): e1001204, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26137396