Detalhe da pesquisa
1.
Structures, Mechanisms, and Functions of His-Me Finger Nucleases.
Trends Biochem Sci
; 45(11): 935-946, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32807610
2.
Lipid-Binding Regions within PKC-Related Serine/Threonine Protein Kinase N1 (PKN1) Required for Its Regulation.
Biochemistry
; 63(6): 743-753, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38441874
3.
Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.
Nucleic Acids Res
; 48(7): 3949-3961, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32083663
4.
Structural insights into nanoRNA degradation by human Rexo2.
RNA
; 25(6): 737-746, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926754
5.
A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication.
Nucleic Acids Res
; 47(10): 5405-5419, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30949702
6.
Tudor staphylococcal nuclease is a structure-specific ribonuclease that degrades RNA at unstructured regions during microRNA decay.
RNA
; 24(5): 739-748, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29440319
7.
Crystal structure of dimeric human PNPase reveals why disease-linked mutants suffer from low RNA import and degradation activities.
Nucleic Acids Res
; 46(16): 8630-8640, 2018 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30020492
8.
Structural insights into RNA unwinding and degradation by RNase R.
Nucleic Acids Res
; 45(20): 12015-12024, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29036353
9.
Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res
; 44(21): 10480-10490, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27738134
10.
Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
PLoS Biol
; 12(3): e1001803, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24594808
11.
Using an Old Drug to Target a New Drug Site: Application of Disulfiram to Target the Zn-Site in HCV NS5A Protein.
J Am Chem Soc
; 138(11): 3856-62, 2016 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26928525
12.
Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res
; 42(16): 10776-85, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25114049
13.
The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Nucleic Acids Res
; 42(7): 4712-22, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464995
14.
The truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.
J Biol Chem
; 288(13): 9049-57, 2013 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23372158
15.
Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation.
Nucleic Acids Res
; 40(9): 4146-57, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22210891
16.
How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes.
Nucleic Acids Res
; 40(16): 8144-54, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22718982
17.
Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans.
J Biol Chem
; 287(10): 7110-20, 2012 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223640
18.
Identification of labile Zn sites in drug-target proteins.
J Am Chem Soc
; 135(38): 14028-31, 2013 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24010488
19.
Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation.
Nat Chem Biol
; 7(4): 236-43, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21317904
20.
Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth.
ACS Chem Biol
; 18(6): 1335-1350, 2023 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188336