Pesquisa | Portal de Pesquisa da BVS

1.

A guide to cell death pathways.

Yuan, Junying; Ofengeim, Dimitry.

Nat Rev Mol Cell Biol ; 25(5): 379-395, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38110635

2.

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.

Xu, Daichao; Jin, Taijie; Zhu, Hong; Chen, Hongbo; Ofengeim, Dimitry; Zou, Chengyu; Mifflin, Lauren; Pan, Lifeng; Amin, Palak; Li, Wanjin; Shan, Bing; Naito, Masanori Gomi; Meng, Huyan; Li, Ying; Pan, Heling; Aron, Liviu; Adiconis, Xian; Levin, Joshua Z; Yankner, Bruce A; Yuan, Junying.

Cell ; 174(6): 1477-1491.e19, 2018 09 06.

Artigo em Inglês | MEDLINE | ID: mdl-30146158

3.

PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.

Hou, Shouqiao; Zhang, Jian; Jiang, Xiaoyan; Yang, Yuanxin; Shan, Bing; Zhang, Mengmeng; Liu, Cong; Yuan, Junying; Xu, Daichao.

Mol Cell ; 84(5): 938-954.e8, 2024 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-38272024

4.

Roles of Caspases in Necrotic Cell Death.

Yuan, Junying; Najafov, Ayaz; Py, Bénédicte F.

Cell ; 167(7): 1693-1704, 2016 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-27984721

5.

Genetic Regulation of RIPK1 and Necroptosis.

Xu, Daichao; Zou, Chengyu; Yuan, Junying.

Annu Rev Genet ; 55: 235-263, 2021 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-34813352

6.

SnapShot: Necroptosis.

Zhou, Wen; Yuan, Junying.

Cell ; 158(2): 464-464.e1, 2014 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-25036639

7.

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.

Najafov, Ayaz; Luu, Hoang Son; Mookhtiar, Adnan K; Mifflin, Lauren; Xia, Hong-Guang; Amin, Palak P; Ordureau, Alban; Wang, Huibing; Yuan, Junying.

Mol Cell ; 81(2): 370-385.e7, 2021 01 21.

Artigo em Inglês | MEDLINE | ID: mdl-33271062

8.

TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL.

Najafov, Ayaz; Mookhtiar, Adnan K; Luu, Hoang Son; Ordureau, Alban; Pan, Heling; Amin, Palak P; Li, Ying; Lu, Qingxian; Yuan, Junying.

Mol Cell ; 75(3): 457-468.e4, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31230815

9.

RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT.

Cao, Ze; Min, Xia; Xie, Xingxing; Huang, Maoqing; Liu, Yingying; Sun, Weimin; Xu, Guifang; He, Miao; He, Kaiwen; Li, Ying; Yuan, Junying.

Proc Natl Acad Sci U S A ; 121(6): e2320383121, 2024 Feb 06.

Artigo em Inglês | MEDLINE | ID: mdl-38289948

10.

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.

Liu, Junli; Xia, Hongguang; Kim, Minsu; Xu, Lihua; Li, Ying; Zhang, Lihong; Cai, Yu; Norberg, Helin Vakifahmetoglu; Zhang, Tao; Furuya, Tsuyoshi; Jin, Minzhi; Zhu, Zhimin; Wang, Huanchen; Yu, Jia; Li, Yanxia; Hao, Yan; Choi, Augustine; Ke, Hengming; Ma, Dawei; Yuan, Junying.

Cell ; 147(1): 223-34, 2011 Sep 30.

Artigo em Inglês | MEDLINE | ID: mdl-21962518

11.

Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.

Yi, Caroline H; Pan, Heling; Seebacher, Jan; Jang, Il-Ho; Hyberts, Sven G; Heffron, Gregory J; Vander Heiden, Matthew G; Yang, Renliang; Li, Fupeng; Locasale, Jason W; Sharfi, Hadar; Zhai, Bo; Rodriguez-Mias, Ricard; Luithardt, Harry; Cantley, Lewis C; Daley, George Q; Asara, John M; Gygi, Steven P; Wagner, Gerhard; Liu, Chuan-Fa; Yuan, Junying.

Cell ; 146(4): 607-20, 2011 Aug 19.

Artigo em Inglês | MEDLINE | ID: mdl-21854985

12.

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.

Xu, Daichao; Zhao, Heng; Jin, Minzhi; Zhu, Hong; Shan, Bing; Geng, Jiefei; Dziedzic, Slawomir A; Amin, Palak; Mifflin, Lauren; Naito, Masanori Gomi; Najafov, Ayaz; Xing, Jing; Yan, Lingjie; Liu, Jianping; Qin, Ying; Hu, Xinqian; Wang, Huibing; Zhang, Mengmeng; Manuel, Vica Jean; Tan, Li; He, Zhuohao; Sun, Zhenyu J; Lee, Virginia M Y; Wagner, Gerhard; Yuan, Junying.

Nature ; 587(7832): 133-138, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32968279

13.

A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1.

Tao, Panfeng; Sun, Jinqiao; Wu, Zheming; Wang, Shihao; Wang, Jun; Li, Wanjin; Pan, Heling; Bai, Renkui; Zhang, Jiahui; Wang, Ying; Lee, Pui Y; Ying, Wenjing; Zhou, Qinhua; Hou, Jia; Wang, Wenjie; Sun, Bijun; Yang, Mi; Liu, Danru; Fang, Ran; Han, Huan; Yang, Zhaohui; Huang, Xin; Li, Haibo; Deuitch, Natalie; Zhang, Yuan; Dissanayake, Dilan; Haude, Katrina; McWalter, Kirsty; Roadhouse, Chelsea; MacKenzie, Jennifer J; Laxer, Ronald M; Aksentijevich, Ivona; Yu, Xiaomin; Wang, Xiaochuan; Yuan, Junying; Zhou, Qing.

Nature ; 577(7788): 109-114, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31827280

14.

Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury.

Li, Yan; Zou, Chengyu; Chen, Chen; Li, Sixuan; Zhu, Ziyu; Fan, Qiuyue; Pang, Rui; Li, Fengshi; Chen, Zengai; Wang, Zhenghong; Yu, Weifeng; Yuan, Junying; Li, Peiying.

Proc Natl Acad Sci U S A ; 120(5): e2219091120, 2023 01 31.

Artigo em Inglês | MEDLINE | ID: mdl-36693098

15.

Small molecule activators of TAK1 promotes its activity-dependent ubiquitination and TRAIL-mediated tumor cell death.

Sun, Weimin; Wu, Guowei; Tian, Xinyu; Qi, Chunting; Liu, Jingli; Tong, Yilun; Zhang, Mengmeng; Gao, Jiayang; Cao, Ze; Zhang, Yuchao; Liu, Zhijun; Tian, Xiaoxu; Wu, Ping; Peng, Chao; Li, Jingwen; Tan, Li; Shan, Bing; Liu, Jianping; Li, Ying; Yuan, Junying.

Proc Natl Acad Sci U S A ; 120(39): e2308079120, 2023 09 26.

Artigo em Inglês | MEDLINE | ID: mdl-37733743

16.

Necroptosis in development and diseases.

Shan, Bing; Pan, Heling; Najafov, Ayaz; Yuan, Junying.

Genes Dev ; 32(5-6): 327-340, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29593066

17.

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death.

Ofengeim, Dimitry; Yuan, Junying.

Nat Rev Mol Cell Biol ; 14(11): 727-36, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24129419

18.

HOIP modulates the stability of GPx4 by linear ubiquitination.

Dong, Kangyun; Wei, Ran; Jin, Taijie; Zhang, Mengmeng; Shen, Jiali; Xiang, Huaijiang; Shan, Bing; Yuan, Junying; Li, Ying.

Proc Natl Acad Sci U S A ; 119(44): e2214227119, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36279464

19.

USP25 regulates Wnt signaling by controlling the stability of tankyrases.

Xu, Daichao; Liu, Jianping; Fu, Tao; Shan, Bing; Qian, Lihui; Pan, Lifeng; Yuan, Junying.

Genes Dev ; 31(10): 1024-1035, 2017 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-28619731

20.

SPATA2 regulates the activation of RIPK1 by modulating linear ubiquitination.

Wei, Ran; Xu, Lily Wen; Liu, Jianping; Li, Yanxia; Zhang, Pei; Shan, Bing; Lu, Xiaojuan; Qian, Lihui; Wu, Zheming; Dong, Kangyun; Zhu, Hong; Pan, Lifeng; Yuan, Junying; Pan, Heling.

Genes Dev ; 31(11): 1162-1176, 2017 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-28701375

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