[DARJELY, a multidisciplinary support system for young isolated migrants in Lyon]. / DARJELY, le dispositif lyonnais d'accompagnement multidisciplinaire des jeunes migrants en errance.

Young, isolated migrants (YIMs) represent some particularly vulnerable populations that have arrived unaccompanied on the national territory and are particularly exposed to mafia networks, delinquency, and prostitution. YIMs thus cumulate social (e.g., precarity, or isolation), psychiatric (e.g., post-traumatic stress disorder, mood, or anxiety disorders), and addiction (e.g., prescription drug dependence) disorders. This addition of vulnerabilities makes the social and medical support difficult to operationalize as it requires multidisciplinary and coordinated programs. In Lyon, the 2nd-largest urban agglomeration in France, the "Dispositif d'accompagnement en Réseau pour l'accès aux soins psychiatriques et addictologiques des jeunes migrants en errance à Lyon" (DARJELY), ("Network System for supporting psychiatric and addiction care to YIMs in Lyon") has been implemented since early 2023 and gathers the following components: (i) a coordinating pair of professionals (i.e., a street worker and an addiction nurse) who ensure a case management of individual situations and articulate the medical and social support with external partners, (ii) an addiction medicine team, (iii) a psychiatric team working at the same place as the addiction medicine team, and (iv) a socio-educational team that can meet YIMs "in situ" and refer them into care, in particular toward teams (ii) and (iii). Overall, DARJELY is thus an innovative system which offers multidisciplinary and coordinated missions toward YIMs including: (i) meeting YIMs on the ground and referring them to specialized care units through the coordination team; (ii) orchestrating the follow-up with other social or medical stakeholders on the local territory; (iii) collecting and synthetizing data for local decision-makers and partners; and (iv) producing research data for improving the understanding of these hard-to-reach populations. All these missions meet current needs of public health regarding these complex populations whose number has been constantly increasing over the recent years.

Perceived ethnic discrimination as a risk factor for psychotic symptoms: a systematic review and meta-analysis.

BACKGROUND: Previous studies have shown an elevated risk of psychotic symptoms (PS) and experiences (PEs) among ethnic minority groups, with significant variation between groups. This pattern may be partially attributable to the unfavorable socio-environmental conditions that surround ethnic minority groups. Perceived ethnic discrimination (PED) in particular has been a salient putative risk factor to explain the increased risk. METHODS: We conducted a systematic literature review and meta-analysis to assess the impact of PED on reporting PS/PEs in ethnic minorities. This review abides by the guidelines set forth by Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The included studies were obtained from the databases: Medline, PsycINFO, and Web Of Science. Sub-group analyses were performed assessing the effect of PED in different subtypes of PS, the influence of ethnicity and moderating/mediating factors. RESULTS: Seventeen studies met the inclusion criteria, and nine were used to conduct the meta-analysis. We found a positive association between PED and the occurrence of PS/PEs among ethnic minorities. The combined odds ratio were 1.77 (95% CI 1.26-2.49) for PS and 1.94 (95% CI 1.42-2.67) for PEs. We found that the association was similar across ethnic groups and did not depend on the ethnic origin of individuals. Weak evidence supported the buffering effects of ethnic identity, collective self-esteem and social support; and no evidence supported the moderating effect of ethnic density. Sensitivity to race-based rejection significantly but only slightly mediated the association. CONCLUSION: These findings suggest that PED is involved in the increased risk of PS/PEs in ethnic minority populations.

Ethnic minority position and migrant status as risk factors for psychotic symptoms in the general population: a meta-analysis.

Psychotic symptoms (PS) are experienced by a substantial proportion of the general population. When not reaching a threshold of clinical relevance, these symptoms are defined as psychotic experiences (PEs) and may exist on a continuum with psychotic disorders. Unfavorable socio-environmental conditions, such as ethnic minority position (EMP) and migrant status (MS), may increase the risk of developing PS and PEs. We conducted an electronic systematic review and a meta-analysis assessing the role of EMP and MS for the development and persistence of PS in the general population. Sub-group analyses were performed investigating the influence of ethnic groups, host countries, age, types of PS, and scales. Twenty-four studies met our inclusion criteria. EMP was a relevant risk factor for reporting PS [odds ratio (OR) 1.44, 95% confidence interval (CI) 1.22-1.70) and PEs (OR 1.36, 95% CI 1.16-1.60). The greatest risk was observed in people from the Maghreb and the Middle East ethnic groups in Europe (OR 3.30, 95% CI 2.09-5.21), in Hispanic in the USA (OR 1.98, 95% CI 1.43-2.73), and in the Black populations (OR 1.85, 95% CI 1.39-2.47). We found a significant association between MS and delusional symptoms (OR 1.47, 95% CI 1.33-1.62). We found no association between EMP and persistence of PEs.EMP was associated with increased risk of reporting PS and PEs, and the risk was higher in ethnic groups facing deprivation and discrimination. We found an association between MS and delusional symptoms. These results raise questions about the precise role of socio-environmental factors along the psychosis continuum.