Detalhe da pesquisa
1.
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Mol Cell
; 82(10): 1821-1835.e6, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35381197
2.
Low-dose metformin targets the lysosomal AMPK pathway through PEN2.
Nature
; 603(7899): 159-165, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197629
3.
Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading in convalescent COVID-19 patients.
Proc Natl Acad Sci U S A
; 119(34): e2117089119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943976
4.
ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy.
Mol Cell
; 62(3): 359-370, 2016 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153534
5.
Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury.
Hepatology
; 67(6): 2397-2413, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29272037
6.
Probucol mitigates high-fat diet-induced cognitive and social impairments by regulating brain redox and insulin resistance.
Front Neurosci
; 18: 1368552, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38716255
7.
Erchen decoction to reduce oxidative stress in dyslipidemia phlegm-dampness retention syndrome mice: In vivo mechanism revealed by metabolomics (liquid chromatography-mass spectrometry).
Phytomedicine
; 115: 154808, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37087794
8.
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
Cell Mol Gastroenterol Hepatol
; 16(4): 541-556, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37331567
9.
Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.
Cell Res
; 33(12): 904-922, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37460805
10.
Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate.
Cell Res
; 33(11): 835-850, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726403
11.
Identification of serum metabolites enhancing inflammatory responses in COVID-19.
Sci China Life Sci
; 65(10): 1971-1984, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508791
12.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Nat Metab
; 4(10): 1369-1401, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36217034
13.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Nat Cell Biol
; 23(3): 268-277, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33664495
14.
Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress.
Cell Res
; 29(6): 460-473, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30948787
15.
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.
Cell Metab
; 30(3): 508-524.e12, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31204282
16.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Cell Metab
; 27(4): 843-853.e6, 2018 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617643
17.
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1.
Cell Res
; 31(4): 478-481, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349646
18.
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cell Res
; 28(8): 865-867, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934617
19.
AMP as a low-energy charge signal autonomously initiates assembly of AXIN-AMPK-LKB1 complex for AMPK activation.
Cell Metab
; 18(4): 546-55, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24093678
20.
The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation.
Cell Res
; 22(8): 1246-57, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22473005