Development of an RNA-protein crosslinker to capture protein interactions with diverse RNA structures in cells.

Characterization of RNA-protein interaction is fundamental for understanding the metabolism and function of RNA. UV crosslinking has been widely used to map the targets of RNA-binding proteins, but is limited by low efficiency, requirement for zero-distance contact, and biases for single-stranded RNA structure and certain residues of RNA and protein. Here, we report the development of an RNA-protein crosslinker (AMT-NHS) composed of a psoralen derivative and an N-hydroxysuccinimide ester group, which react with RNA bases and primary amines of protein, respectively. We show that AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. The crosslinker induced different crosslinking patterns than UV and targeted both single- and double-stranded regions of RNA. The crosslinker provides a new tool to capture diverse RNA-protein interactions in cells.

Quantum squeezing-induced quantum entanglement and EPR steering in a coupled optomechanical system.

We propose a theoretical project in which quantum squeezing induces quantum entanglement and Einstein-Podolsky-Rosen steering in a coupled whispering-gallery-mode optomechanical system. Through pumping the χ(2)-nonlinear resonator with the phase matching condition, the generated squeezed resonator mode and the mechanical mode of the optomechanical resonator can generate strong quantum entanglement and EPR steering, where the squeezing of the nonlinear resonator plays the vital role. The transitions from zero entanglement to strong entanglement and one-way steering to two-way steering can be realized by adjusting the system parameters appropriately. The photon-photon entanglement and steering between the two resonators can also be obtained by deducing the amplitude of the driving laser. Our project does not need an extraordinarily squeezed field, and it is convenient to manipulate and provides a novel and flexible avenue for diverse applications in quantum technology dependent on both optomechanical and photon-photon entanglement and steering.

Optical characterization of a fiber Fabry-Perot cavity: precision measurement of intra-cavity loss, transmittance, and reflectance.

We propose and demonstrate a method for characterizing the individual mirror parameters of a fiber Fabry-Perot cavity (FFPC). By measuring the reflection and transmission spectra of the FFPC with an incident laser propagating from the two mirrors of the FFPC and considering several normal or unique losses, the transmittance, reflectance, and intra-cavity loss of the individual mirrors can be determined. Due to the intrinsic limitation of cavity length, traditional powerful methods, such as the cavity ring-down technique, are not applicable to FFPCs for characterizing the parameters of individual mirrors. This scheme provides a dependable method for assessing FFPC mirrors and provides a significant capability for the implementation of strong-coupling cavity quantum electrodynamics based on FFPCs.

Resolved Raman sideband cooling of a single optically trapped cesium atom.

We developed a resolved Raman sideband cooling scheme that can efficiently prepare a single optically trapped cesium (Cs) atom in its motional ground states. A two-photon Raman process between two outermost Zeeman sublevels in a single hyperfine state is applied to reduce the phonon number. Our scheme is less sensitive to the variation in the magnetic field than the commonly used scheme where the two outermost Zeeman sublevels belonging to the two separate ground hyperfine states are taken. Fast optical pumping with less spontaneous emission guarantees the efficiency of the cooling process. After cooling for 50 ms, 82% of the Cs atoms populate their three-dimensional ground states. Our scheme improves the long-term stability of Raman sideband cooling in the presence of magnetic field drift and is thus suitable for cooling other trapped atoms or ions with abundant magnetic sublevels.

Measurement of Nanofiber Mechanical Flexural Modes Based on Near-Field Scattering.

We systematically investigated the intrinsic mechanical flexural modes of tapered optical fibers (TOFs) with a high aspect ratio up to 3×10^{4}. Based on the near-field scattering of the hemispherical microfiber tip to the vibrating TOF evanescent field, we detected more than 320 ordered intrinsic mechanical modes through the TOF transmission spectra which was enhanced by 72 dB compared to without near-field scattering. The trend of the vibration amplitude with the mode order was similar to pendulum waves. Our results open a pathway to study the mechanical modes of photonic microstructures-nanostructures that are expected to be used in waveguide QED, cavity optomechanical, and optical sensing.

Hexapartite steering based on a four-wave-mixing process with a spatially structured pump.

Multipartite Einstein-Podolsky-Rosen (EPR) steering has been widely studied, for realizing safer quantum communication. The steering properties of six spatially separated beams from the four-wave-mixing process with a spatially structured pump are investigated. Behaviors of all (1+i)/(i+1)-mode (i=1,2,3) steerings are understandable, if the role of the corresponding relative interaction strengths are taken into account. Moreover, stronger collective multipartite steerings including five modes can be obtained in our scheme, which has potential applications in ultra-secure multiuser quantum networks when the issue of trust is critical. By further discussing about all monogamy relations, it is noticed that the type-IV monogamy relations, which are naturally included in our model, are conditionally satisfied. Matrix representation is used to express the steerings for the first time, which is very useful to understand the monogamy relations intuitively. Different steering properties obtained in this compact phase-insensitive scheme have potential applications for different kinds of quantum communication tasks.

Generation of multipartite entangled states based on a double-longitudinal-mode cavity optomechanical system.

An optomechanical system is a promising platform to connect different "notes" of quantum networks. Therefore, entanglements generated from it is also of great importance. In this paper, the parameter dependence of optomechanical and optical-optical entanglements generated from the double-longitudinal-mode cavity optomechanical system are discussed and two quadrapartite entanglement generation schemes based on such a system are proposed. Furthermore, 2N and 4N-partite entangled states of optical modes can be obtained by coupling N cavities that used in the above two schemes with N-1 beamsplitters, respectively. Certain ladder or linear entanglement structures are included in the finally obtained entangled state, which are important for its application in one-way quantum computing.

Cavity-enhanced optical bistability of Rydberg atoms.

Optical bistability (OB) of Rydberg atoms provides a new, to the best of our knowledge, platform for studying nonequilibrium physics and a potential resource for precision metrology. To date, the observation of Rydberg OB has been limited in free space. Here, we explore cavity-enhanced Rydberg OB with a thermal cesium vapor cell. The signal of Rydberg OB in a cavity is enhanced by more than one order of magnitude compared with that in free space. The slope of the phase transition signal at the critical point is enhanced more than 10 times that without the cavity, implying an enhancement of two orders of magnitude in the sensitivity for Rydberg-based sensing and metrology.

Realization of Strong Coupling between Deterministic Single-Atom Arrays and a High-Finesse Miniature Optical Cavity.

We experimentally demonstrate strong coupling between a one-dimensional (1D) single-atom array and a high-finesse miniature cavity. The atom array is obtained by loading single atoms into a 1D optical tweezer array with dimensions of 1×11. Therefore, a deterministic number of atoms is obtained, and the atom number is determined by imaging the atom array on a CCD camera in real time. By precisely controlling the position and spacing of the atom array in the high finesse Fabry-Perot cavity, all the atoms in the array are strongly coupled to the cavity simultaneously. The vacuum Rabi splitting spectra are discriminated for deterministic atom numbers from 1 to 8, and the sqrt[N] dependence of the collective enhancement of the coupling strength on atom number N is validated at the single-atom level.

High-order continuous-variable coherence of phase-dependent squeezed state.

We study continuous variable coherence of phase-dependent squeezed state based on an extended Hanbury Brown-Twiss scheme. High-order coherence is continuously varied by adjusting squeezing parameter r, displacement α, and squeezing phase θ. We also analyze effects of background noise γ and detection efficiency η on the measurements. As the squeezing phase shifts from 0 to π, the photon statistics of the squeezed state continuously change from the anti-bunching (g(n) < 1) to super-bunching (g(n) > n!) which shows a transition from particle nature to wave nature. The experiment feasibility is also examined. It provides a practical method to generate phase-dependent squeezed states with high-order continuous-variable coherence by tuning squeezing phase θ. The controllable coherence source can be applied to sensitivity improvement in gravitational wave detection and quantum imaging.

Optical spectrum detection of synthetic microsphere resonator using a nanofiber.

We demonstrate optical spectrum detection of a synthetic silica microsphere (SSM) resonator with whispering gallery modes fabricated by chemical methods using an optical nanofiber to touch the SSM. Critical coupling, under coupling and over coupling are obtained by controlling the nanofiber radius. The SSM radius deviation, 0.51 nm, can be obtained through multiple measurements when the nanofiber touches the SSM equatorial planes randomly. The scheme opens a new avenue for accurate sample characterization and sample tracking for microparticle detection.

Mechanical squeezing in an active-passive-coupled double-cavity optomechanical system via pump modulation.

We focus on the generation of mechanical squeezing by using periodically amplitude-modulated laser to drive an active-passive-coupled double-cavity optomechanical system, where the coupled gain cavity and loss cavity can form into a parity-time (P T)-symmetry system. The numerical analysis of the system stability shows that the system is more likely to be stable in the unbroken-P T-symmetry regime than in the broken-P T-symmetry regime. The mechanical squeezing in the active-passive system exhibits stronger robustness against the thermal noise than that in the passive-passive system, and the so-called 3 dB limit can be broken in the resolved-sideband regime. Furthermore, it is also found that the mechanical squeezing obtained in the unbroken-P T-symmetry region is stronger than that in the broken-P T-symmetry region. This work may be meaningful for the quantum state engineering in the gain-loss quantum system that contributes to the study of P T-symmetric physics in the quantum regime.

Monolithic mode separator for the first-order spatial mode of light field.

We propose a monolithic mode separator (MS) for the first-order spatial mode of a light field. The principle of the MS is an asymmetric Mach-Zehnder interferometer, which consists of two non-polarizing beam splitters, a right-angle prism, and a pentagonal prism. These optics are glued together as a monolithic one. The phase difference between the two light paths inside the interferometer is temperature controlled. The separation efficiency for two first-order orthogonal Hermite Gaussian (HG) modes, i.e., HG01 and HG10, is 97.5%, and the overall transmission is 77%. The device is intrinsically stable and convenient to be adopted in various experiments.

Unmanned Aerial Vehicle (UAV) Robot Microwave Imaging Based on Multi-Path Scattering Model.

Unmanned Aerial Vehicle (UAV) robot microwave imaging systems have attracted comprehensive attention. Compared with visible light and infrared imaging systems, microwave imaging is not susceptible to weather. Active microwave imaging systems have been realized in UAV robots. However, the scattering signals of geographical objects from satellite transmitting systems received by UAV robots to process imaging is studied rarely, which reduces the need of load weight for the UAV robot. In this paper, a multi-path scattering model of vegetation on the earth surface is proposed, and then the microwave imaging algorithm is introduced to reconstruct the images from the UAV robot receiving the scattering data based on the multi-path model. In image processing, it is assumed that the orbit altitude of a transmitter loaded on the satellite remains unchanged, and the receiver loaded UAV robot obtains the reflective information from ground vegetation with different zenith angles. The imaging results show that the angle change has an impact on the imaging resolution. The combination of electromagnetic scattering model and image processing method contributes to understanding the image results and the multi-path scattering mechanisms of vegetation, which provide a reference for the research and development of microwave imaging systems of UAV robot networking using satellite transmitting signals.

High-efficiency coupling of single quantum emitters into hole-tailored nanofibers.

We propose a scheme to enhance the coupling efficiency of photons from a single quantum emitter into a hole-tailored nanofiber. The single quantum emitter is positioned inside a circular hole etched along the radial axis of the nanofiber. The coupling efficiency can be effectively enhanced and is twice as high as the case in which only an intact nanofiber without the hole is used. The effective enhancement independent of a cavity can avoid the selection of a single emitter for the specific wavelength, which means a broad operating wavelength range. Numerical simulations are performed to optimize the coupling efficiency by setting appropriate diameters of the nanofiber and the hole. The simulation results show that the coupling efficiency can reach 62.8% when the single quantum emitter with azimuthal polarization (x direction) is at a position 200 nm from the middle of the hole along the hole-axial direction. The diameters of the nanofiber and the hole are 800 nm and 400 nm, respectively, while the wavelength of the single quantum emitter is 852 nm. Hole-tailored nanofibers have a simple configuration and are easy to fabricate and integrate with other micro/nanophotonic structures; this fiber structure has wide application prospects in quantum information processing and quantum precision measurement.

Versatile objectives with NA = 0.55 and NA = 0.78 for cold-atom experiments.

We present two sets of versatile high-numerical-apeture objectives suitable for various cold-atom experiments. The objectives are assembled entirely by the commercial on-shelf singlets. The two objectives are initially optimized at working wavelength of 852 nm with a standard 5-mm silica optical flat window. They have numerical apertures of NA=0.55 and NA=0.78, working distances of 23 and 12.8 mm, diffraction-limited fields of view of 98 and 15 µm, and spatial resolutions of 0.94 and 0.67 µm, respectively. These performances are simulated by the ray-tracing software and experimentally confirmed by imaging line patterns and a point-like emitter on a resolution chart. The two objectives can be further reoptimized at any single wavelengths from ultraviolet to near infrared and for various optical flat window with different thickness by only tuning one of lens spacing. The two objectives provide convenient and flexible options to observe and address individual atoms in single atom arrays or optical lattices for various cold-atom experiments.

Triply Magic Conditions for Microwave Transition of Optically Trapped Alkali-Metal Atoms.

We report the finding of "triply magic" conditions (the doubly magic frequency-intensity conditions of an optical dipole trap plus the magic magnetic field) for the microwave transitions of optically trapped alkali-metal atoms. The differential light shift (DLS) induced by a degenerate two-photon process is adopted to compensate a DLS associated with the one-photon process. Thus, doubly magic conditions for the intensity and frequency of the optical trap beam can be found. Moreover, the DLS decouples from the magnetic field in a linearly polarized optical dipole trap, so that the magic condition of the magnetic field can be applied independently. Therefore, the triply magic conditions can be realized simultaneously. We also experimentally demonstrate the doubly magic frequency-intensity conditions as well as the independence of the magnetic field. When the triply magic conditions are fulfilled, the inhomogeneous and homogeneous decoherences for the optically trapped atom will be dramatically suppressed, and the coherence time can be extended significantly.

Realization of Nonlinear Optical Nonreciprocity on a Few-Photon Level Based on Atoms Strongly Coupled to an Asymmetric Cavity.

Optical nonreciprocity is important in photonic information processing to route the optical signal or prevent the reverse flow of noise. By adopting the strong nonlinearity associated with a few atoms in a strongly coupled cavity QED system and an asymmetric cavity configuration, we experimentally demonstrate the nonreciprocal transmission between two counterpropagating light fields with extremely low power. The transmission of 18% is achieved for the forward light field, and the maximum blocking ratio for the reverse light is 30 dB. Though the transmission of the forward light can be maximized by optimizing the impedance matching of the cavity, it is ultimately limited by the inherent loss of the scheme. This nonreciprocity can even occur on a few-photon level due to the high optical nonlinearity of the system. The working power can be flexibly tuned by changing the effective number of atoms strongly coupled to the cavity. The idea and result can be applied to optical chips as optical diodes by using fiber-based cavity QED systems. Our work opens up new perspectives for realizing optical nonreciprocity on a few-photon level based on the nonlinearities of atoms strongly coupled to an optical cavity.

Nondestructive measurement of nanofiber diameters using microfiber tip.

We demonstrate a convenient and simple method to determine nanofiber diameters nondestructively using a hemispherical microfiber tip probe. For a fixed-tip geometry and working wavelength, the scattering losses of nanofiber transmission induced by the tip are a function of the nanofiber diameter, while being insensitive to the alignment. Therefore, the nanofiber diameter can be estimated based on the measured nanofiber transmittance and the loss-diameter relationship that are obtained by three-dimensional numerical simulations. The method is experimentally demonstrated with a diameter measurement precision of 9.8 nm (1.5% of the measured diameter), and the results agree with those obtained by other methods. Such a nondestructive near-field probe approach offers a reliable and convenient technique for determining nanofiber diameters, with applications ranging from optical sensing to quantum optics to quantum information processing.

Quantum delayed-choice experiment with a single neutral atom.

We present a proposal to implement a quantum delayed-choice (QDC) experiment with a single neutral atom, such as a rubidium or cesium atom. In our proposal, a Ramsey interferometer is adopted to observe the wave-like or particle-like behaviors of a single atom depending on the existence or absence of the second π/2-rotation. A quantum-controlled π/2-rotation on target atom is realized through a Rydberg-Rydberg interaction by another ancilla atom. It shows that a heavy neutral atom can also have a morphing behavior between the particle and the wave. The realization of the QDC experiment with such heavy neutral atoms not only is significant to understand the Bohr's complementarity principle in matter-wave and matter-particle domains but also has great potential on the quantum information process with neutral atoms.