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1.
J Biomed Inform ; 102: 103360, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31904428

RESUMO

Clustering data derived from Electronic Health Record (EHR) systems is important to discover relationships between the clinical profiles of patients and as a preprocessing step for analysis tasks, such as classification. However, the heterogeneity of these data makes the application of existing clustering methods difficult and calls for new clustering approaches. In this paper, we propose the first approach for clustering a dataset in which each record contains a patient's values in demographic attributes and their set of diagnosis codes. Our approach represents the dataset in a binary form in which the features are selected demographic values, as well as combinations (patterns) of frequent and correlated diagnosis codes. This representation enables measuring similarity between records using cosine similarity, an effective measure for binary-represented data, and finding compact, well-separated clusters through hierarchical clustering. Our experiments using two publicly available EHR datasets, comprised of over 26,000 and 52,000 records, demonstrate that our approach is able to construct clusters with correlated demographics and diagnosis codes, and that it is efficient and scalable.


Assuntos
Registros Eletrônicos de Saúde , Análise por Conglomerados , Demografia , Humanos
2.
Neural Netw ; 180: 106653, 2024 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-39191126

RESUMO

Recently, Vision Transformer and its variants have demonstrated remarkable performance on various computer vision tasks, thanks to its competence in capturing global visual dependencies through self-attention. However, global self-attention suffers from high computational cost due to quadratic computational overhead, especially for the high-resolution vision tasks (e.g., object detection and semantic segmentation). Many recent works have attempted to reduce the cost by applying fine-grained local attention, but these approaches cripple the long-range modeling power of the original self-attention mechanism. Furthermore, these approaches usually have similar receptive fields within each layer, thus limiting the ability of each self-attention layer to capture multi-scale features, resulting in performance degradation when handling images with objects of different scales. To address these issues, we develop the Diagonal-shaped Window (DiagSWin) attention mechanism for modeling attentions in diagonal regions at hybrid scales per attention layer. The key idea of DiagSWin attention is to inject multi-scale receptive field sizes into tokens: before computing the self-attention matrix, each token attends its closest surrounding tokens at fine granularity and the tokens far away at coarse granularity. This mechanism is able to effectively capture multi-scale context information while reducing computational complexity. With DiagSwin attention, we present a new variant of Vision Transformer models, called DiagSWin Transformers, and demonstrate their superiority in extensive experiments across various tasks. Specifically, the DiagSwin Transformer with a large size achieves 84.4% Top-1 accuracy and outperforms the SOTA CSWin Transformer on ImageNet with 40% fewer model size and computation cost. When employed as backbones, DiagSWin Transformers achieve significant improvements over the current SOTA modules. In addition, our DiagSWin-Base model yields 51.1 box mAP and 45.8 mask mAP on COCO for object detection and segmentation, and 52.3 mIoU on the ADE20K for semantic segmentation.

3.
IEEE J Biomed Health Inform ; 26(5): 2351-2359, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-34797768

RESUMO

A Relational-Sequential dataset (or RS-dataset for short) contains records comprised of a patient's values in demographic attributes and their sequence of diagnosis codes. The task of clustering an RS-dataset is helpful for analyses ranging from pattern mining to classification. However, existing methods are not appropriate to perform this task. Thus, we initiate a study of how an RS-dataset can be clustered effectively and efficiently. We formalize the task of clustering an RS-dataset as an optimization problem. At the heart of the problem is a distance measure we design to quantify the pairwise similarity between records of an RS-dataset. Our measure uses a tree structure that encodes hierarchical relationships between records, based on their demographics, as well as an edit-distance-like measure that captures both the sequentiality and the semantic similarity of diagnosis codes. We also develop an algorithm which first identifies k representative records (centers), for a given k, and then constructs k clusters, each containing one center and the records that are closer to the center compared to other centers. Experiments using two Electronic Health Record datasets demonstrate that our algorithm constructs compact and well-separated clusters, which preserve meaningful relationships between demographics and sequences of diagnosis codes, while being efficient and scalable.


Assuntos
Algoritmos , Registros Eletrônicos de Saúde , Análise por Conglomerados , Demografia , Humanos , Semântica
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