Detalhe da pesquisa
1.
Unlocking the potential of protein-derived peptides to target G-quadruplex DNA: from recognition to anticancer activity.
Nucleic Acids Res
; 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38828773
2.
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.
EMBO J
; 38(11)2019 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000523
3.
Selective Targeting of Cancer-Related G-Quadruplex Structures by the Natural Compound Dicentrine.
Int J Mol Sci
; 24(4)2023 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36835480
4.
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein.
Nucleic Acids Res
; 47(18): 9950-9966, 2019 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31504744
5.
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.
Nucleic Acids Res
; 47(7): 3365-3382, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698737
6.
Synthesis and Characterization of Bis-Triazolyl-Pyridine Derivatives as Noncanonical DNA-Interacting Compounds.
Int J Mol Sci
; 22(21)2021 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769387
7.
Trifunctionalized Naphthalene Diimides and Dimeric Analogues as G-Quadruplex-Targeting Anticancer Agents Selected by Affinity Chromatography.
Int J Mol Sci
; 21(6)2020 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183038
8.
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Nucleic Acids Res
; 45(4): 1820-1834, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27923994
9.
The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses.
J Biol Chem
; 292(31): 12828-12841, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600357
10.
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
Nucleic Acids Res
; 44(4): 1579-90, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26511095
11.
EMICORON: A multi-targeting G4 ligand with a promising preclinical profile.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1362-1370, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27838395
12.
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1341-1352, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28130159
13.
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Nucleic Acids Res
; 43(3): 1759-69, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25618850
14.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Nucleic Acids Res
; 42(5): 2945-57, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335081
15.
Shading the TRF2 recruiting function: a new horizon in drug development.
J Am Chem Soc
; 136(48): 16708-11, 2014 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393214
16.
Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage.
Org Biomol Chem
; 12(47): 9572-82, 2014 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25363232
17.
TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication.
J Exp Clin Cancer Res
; 43(1): 75, 2024 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38459559
18.
Phospholipase A2IVα regulates phagocytosis independent of its enzymatic activity.
J Biol Chem
; 287(20): 16849-59, 2012 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393044
19.
The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy.
Autophagy
; 19(5): 1479-1490, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36310382
20.
Drug repositioning strategy for the identification of novel telomere-damaging agents: A role for NAMPT inhibitors.
Aging Cell
; 22(11): e13944, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858982