Detalhe da pesquisa
1.
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
Nature
; 608(7923): 609-617, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948633
2.
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.
Nature
; 572(7770): 538-542, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31367040
3.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
EMBO J
; 39(5): e102169, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930530
4.
Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.
Nucleic Acids Res
; 50(13): 7420-7435, 2022 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35819193
5.
Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.
Nature
; 609(7929): E13, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050473
6.
Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer.
Breast Cancer Res
; 24(1): 41, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35715861
7.
Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.
Proc Natl Acad Sci U S A
; 112(27): 8409-14, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100884
8.
Loss of the volume-regulated anion channel components LRRC8A and LRRC8D limits platinum drug efficacy.
Cancer Res Commun
; 2(10): 1266-1281, 2022 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36467895
9.
A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.
Cancer Res
; 81(24): 6171-6182, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548335
10.
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.
Cell Rep
; 32(8): 108068, 2020 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32846126
11.
Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.
Cancer Res
; 79(3): 452-460, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530501
12.
Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547.
Cancer Res
; 78(19): 5668-5679, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30115694