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Cir Cir ; 78(4): 310-4, 2010.
Artigo em Espanhol | MEDLINE | ID: mdl-21167096

RESUMO

BACKGROUND: Approximately 30% of women who undergo mastectomy without reconstructive treatment due to breast cancer present sequelae. These include paresthesias, keloid healing, hypoesthesia, lymphedema and limitation of the function of the ipsilateral upper extremity. We undertook this study to present the results using collagen-polyvinylpyrrolidone (Clg- Pvp) as treatment for posmastectomy sequelae in women with breast cancer. METHODS: We conducted a unicentric, longitudinal and prospective clinical trial between August 1, 2007 and July 31, 2008. Included variables were age, lymphedema, limitation of the function of the ipsilateral upper extremity, collapse of the wound, keloid healing, paresthesias, and appearance of the surgical area. The appearance of the surgical area (aesthetic aspect) was evaluated before and 6 months after treatment was initiated. Clg-Pvp was administered weekly for a 6-month period. RESULTS: Seven women were included with a median age of 49 years (range: 40-72 years). One patient (14.28%) presented lymphedema, two patients (28.57%) presented collapse of the wound, two patients (28.57%) had keloid healing, three patients (42.85%) experienced paresthesias, five patients (71.4%) reported pain, and five patients (71.4%) reported limitation of the function of the ipsilateral upper extremity. At the completion of the treatment, aesthetic improvement was statistically significant (p = 0.0020, Mann-Whitney U test). CONCLUSIONS: Clinical and aesthetic results are good after application of Clg-Pvp for treating sequelae in women with breast cancer who underwent mastectomy without reconstructive surgery.


Assuntos
Neoplasias da Mama/cirurgia , Cicatriz/prevenção & controle , Colágeno/uso terapêutico , Fármacos Dermatológicos/uso terapêutico , Excisão de Linfonodo/efeitos adversos , Linfedema/prevenção & controle , Mastectomia Radical/efeitos adversos , Parestesia/prevenção & controle , Povidona/uso terapêutico , Adulto , Idoso , Braço , Cicatriz/etiologia , Colágeno/administração & dosagem , Colágeno/farmacologia , Fármacos Dermatológicos/administração & dosagem , Estética , Feminino , Humanos , Injeções Subcutâneas , Queloide/etiologia , Queloide/prevenção & controle , Linfedema/etiologia , Pessoa de Meia-Idade , Parestesia/etiologia , Povidona/administração & dosagem , Povidona/farmacologia , Estudos Prospectivos , Amplitude de Movimento Articular , Cicatrização/efeitos dos fármacos
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