RESUMO
Despite a significant increasing trend in historical food grain production (FGP) in India, deficient Indian summer monsoon rainfall (ISMR) often causes a reduction in FGP. The present study was carried out to understand temporal and spatial variations in deficient rainfall (drought) and their impact on national and regional FGP of India. Long-term (1901-2020) percentage departure in rainfall and drought areas over the country showed nonsignificant and significant trends, respectively. Subdivisional rainfall showed significant decreasing and increasing trends in 4 and 5 subdivisions, respectively. Drought years of high frequency (once in 3-4 years) and 4 to 5 consecutive drought years (once in 120 years) occurred in northwest and western subdivisions of India. Departure in de-trended production of All India Kharif food grains from its normal (DDP) showed significant quadratic relationship with departure in ISMR from its normal (DRF). Besides the quadratic equation, another multiple regression model taking de-trended crop area, DRF, and drought area as predictor variables was developed for predicting DDP. Both these models, with high R2 (0.8-0.88) between observed and predicted data and low RMSE (2.6-2.7%), can be employed for advanced estimation of DDP of the country and for taking country-level policy decisions by the Indian Government. For the first time, models were formulated to estimate state-wise departure in FGP (DP). In these models, novel indices viz., (i) rainfall departure and irrigation index (RDII) and (ii) physical and socio-economic index (PSEI), were used as predictor variables. These models, with R2 (0.71-0.75) and RMSE of 11.8-14.2(< SD of observed data), hold promise for advance estimation of production loss in states, useful for regional-level planning by the Government of India, and testing them in other countries.
Assuntos
Monitoramento Ambiental , Chuva , Estações do Ano , Grão Comestível , ÍndiaRESUMO
Campylobacter jejuni PseI is a pseudaminic acid synthase that condenses the 2,4-diacetamido-2,4,6-trideoxy-l-altrose sugar (6-deoxy AltdiNAc) and phosphoenolpyruvate to generate pseudaminic acid, a sialic acid-like 9-carbon backbone α-keto sugar. Pseudaminic acid is conjugated to cell surface proteins and lipids and plays a key role in the mobility and virulence of C. jejuni and other pathogenic bacteria. To provide insights into the catalytic mechanism of PseI, we performed a structural study on PseI. PseI forms a two-domain structure and assembles into a domain-swapped homodimer. The PseI dimer has two cavities, each of which accommodates a metal ion using conserved histidine residues. A comparative analysis of structures and sequences suggests that the cavity of PseI functions as an active site that binds the 6-deoxy AltdiNAc and phosphoenolpyruvate substrates and mediates their condensation. Furthermore, we propose the substrate binding-induced structural rearrangement of PseI and predict 6-deoxy AltdiNAc recognition residues that are specific to PseI.