A review of hair removal modalities in pediatric patients: Ethical and clinical considerations.

Unwanted hair is a common concern among patients presenting to pediatric dermatology clinics, and parents and patients alike inquire about the safety of methods employed for elective removal. Various methods of hair removal exist with different levels of invasiveness and permanence, from simple mechanical depilation to light-based therapies. All methods of hair removal appear to be safe and generally well tolerated in children, and there are no age restrictions to any modality. In this review, we aim to address the available literature on the safety and efficacy of hair removal modalities in pediatric patients and propose guidance on how to manage requests for at-home and in-office therapies within an ethical framework.

Optimized Depilation Method and Comparative Analysis of Hair Growth Cycle in Mouse Strains.

In mice, hair growth follows a mosaic or wavy patterning. Therefore, synchronization of the hair growth cycle is required to adequately evaluate any trichogenic interventions pre-clinically. Depilation is the established method for synchronizing the growth phase of mouse hair follicles. When attempting to reproduce procedures reported in the literature, C57BL/6J mice developed severe wounds. This led us not only to optimize the procedure, but also to test the procedure in other strains, namely Sv129 and the F1 generation from C57BL/6J crossed with Sv129 (B6129F1 mixed background), for which the hair growth cycle has not been ascertained yet. Here, we describe an optimized depilation procedure, using cold wax and an extra step to protect the animal skin that minimizes injury, improving experimental conditions and animal welfare in all strains. Moreover, our results show that, although hair cycle kinetics are similar in all the analyzed strains, Sv129 and B6129F1 skins are morphologically different from C57BL/6J skin, presenting an increased number and size of hair follicles in anagen, consistent to the higher hair density observed macroscopically. Altogether, the results disclose an optimized mouse depilation method that excludes the detrimental and confounding effects of skin injury in hair growth studies and reveals the hair cycle features of other mouse strains, supporting their use in hair growth pre-clinical studies.

The Preference of Women and Men Regarding Female Genital Depilation / A preferência de mulheres e homens em relação à depilação genital feminina

Abstract Purpose To evaluate the preferences of women and men regarding female pubic hair depilation and identify possible reasons for these preferences. Methods This is a cross-sectional study of men and women over 18 years old who were invited by the official blog of our institution to respond anonymously to an online and self-administered questionnairemade by the researchers. The analyses weremade using the Statistical Analysis System (SAS, SAS Inc., Cary, NC, US) software, version 9.3, and contingency tables were used to verify the distribution of variables. The univariate statistical analysis was performed using the Pearson chi-squared test, and the differences for values of p < 0.05 were considered significant. Results We obtained data from 69,920 subjects (52,787 women and 17,133 men). Themean age was 31.9 years formen, and 28.5 years for women. Most women (64.3%) and men (62.2%) preferred complete removal of female pubic hair, and this preference wasmore pronounced in younger women andmen. Most women reported performing depilation at home (55.8%), with 44.4% using hot wax and 40.1% using a razor blade. About half of the women (44.7%) and men (50.1%) reported sexual activity, having intercourse 2 to 3 times per week. The frequency of intercourse and sexual satisfaction in women correlated with total pubic hair removal. Conclusion Most Brazilian women and men prefer the complete removal of female pubic hair, especially those who are younger andmore sexually active.Women who are satisfied with the appearance of their own genitalia have a stronger preference for complete removal of pubic hair.

Resumo Objetivos Avaliar a preferência de mulheres e homens emrelação à depilação genital feminina, e identificar possíveis razões envolvidas nessa preferência. Método Estudo transversal em que homens e mulheres com mais de 18 anos foram convidados por meio do blog oficial de nossa instituição a responder anonimamente a um formulário on-line e autoadministrado de autoria dos pesquisadores. As análises foram realizadas no programa Statistical Analysis System (SAS, SAS Inc., Cary, Carolina do Norte, EUA), versão 9.3, e tabelas de contingência foram construídas para verificar a distribuição entre as variáveis. A análise estatística univariada foi realizada com o teste qui-quadrado de Pearson, e foram consideradas significativas as diferenças para p < 0,05. Resultados Foram obtidos dados de 69.920 indivíduos (52.787 mulheres e 17.133 homens). A idade média dos indivíduos foi de 31,9 anos entre os homens, e de 28,5 entre as mulheres. A maioria das mulheres (64,3%) e dos homens (62,2%) preferiram a genitália feminina completamente depilada, e essa preferência foi mais pronunciada em mulheres e homens mais jovens. A maioria das mulheres afirmaram se depilar em casa (55,8%), e 44,4% delas usam cera quente, e 40,1% utilizam lâmina de barbear. Quase metade das mulheres (44,7%) e metade dos homens (50,1%) alegaram ter frequência sexual de 2 a 3 vezes por semana. A frequência sexual das mulheres e a satisfação com sua própria genitália foram positivamente relacionadas com a preferência pela remoção total dos pelos pubianos. Conclusões A maioria das mulheres e dos homens brasileiros preferem a remoção completa dos pelos genitais femininos, o que é ainda mais pronunciado nos indivíduos mais jovens e sexualmente ativos. As mulheres satisfeitas com a aparência de sua própria genitália tendem a preferir a remoção completa dos pelos pubianos.