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1.
Ann Plast Surg ; 93(2S Suppl 1): S4-S10, 2024 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-38896857

RESUMO

BACKGROUND: An increasing number of surgical and nonsurgical interventions are available in the field of female genital plastic surgery. The rate of female genital plastic surgery has increased by nearly 220 percent over the past 5 years. Despite several studies on the topic, no relevant bibliometric analysis has been conducted. METHODS: We searched the Web of Science Core Collection for articles related to female genital plastic surgery. CiteSpace 6.1.R2 (Drexel University, USA) and VOSviewer 1.6.10.0 (Leiden University, the Netherlands) were used, and national distribution, institutions, journals, authors, and key words were analyzed and calculated. RESULTS: From 2003 to 2022, 1299 papers in the field of female genital plastic surgery were retrieved. There were more articles produced in the United States, and there were also two institutions in the Netherlands that were highly productive. A wide and close relationship has been established between researchers and institutions conducting female genital plastic surgery. Professor Bouman MB published the most articles on female genital plastic surgery in the Journal of Sexual Medicine. Female genital plastic surgery dominated the top 10 references with the highest local citation score. There were four clusters of key words with the most citations, and the most recently trending key words were "vaginal agenesis," "transgender," and "congenital adrenal hyperplasia." CONCLUSIONS: The purpose of this article is to provide a summary of the current research status focusing on female genital plastic surgery. It is hoped that more efforts will be made to promote the development of female genital plastic surgery in the future.


Assuntos
Bibliometria , Cirurgia Plástica , Humanos , Feminino , Cirurgia Plástica/estatística & dados numéricos , Cirurgia Plástica/tendências , Procedimentos de Cirurgia Plástica/estatística & dados numéricos , Procedimentos Cirúrgicos em Ginecologia/estatística & dados numéricos , Genitália Feminina/cirurgia
2.
Aesthetic Plast Surg ; 48(15): 2975-2993, 2024 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38671242

RESUMO

BACKGROUND AND OBJECTIVES: Due to the increasing demand for improving the morphology and function of the external genitalia amongst women, it is necessary to conduct statistical analysis of research data on female genital reconstruction. The current study aimed to use bibliometric analysis to analyse the research hotspots and trend frontiers of the female genital reconstructive research. METHODS: Publications on the female genital reconstructive research were extracted from the Web of Science Core Collection database. VOSviewer 1.6.18 was used to establish visualisation maps and find top authors, institutions, countries, burst keywords, co-cited authors, journals, research hotspots, and trends. RESULTS: A total of 2207 studies published by 364 different journals authored by 7479 researchers were contained in this study. In the co-authorship analysis, the bulk of the retrieved studies was conducted by the USA, followed by England, Italy, and Netherlands, whilst the most productive institution, journal, and author were U.S. Univ Calif San Francisco, Journal of Sexual Medicine, and Bouman Mark-Bram, respectively. In the co-cited analysis, the top most-cited author and journal were Hage JJ and Journal of Sexual Medicine, respectively. The map of keywords occurrence revealed the most active research aspects were focussed on "vaginoplasty", "feminised genitoplasty", "laser treatment of vaginal atrophy", "transsexualism", and "labiaplasty". The time overlay mapping showed that the study of female genital plastic surgery focusses on the energetic treatment of genitourinary syndromes caused by transsexualism and menopause, especially by using management and treatment of vulvovaginal atrophy for the research trends, and through the vaginoplasty, feminising genioplasty, and laser treatments in the direction of treatments related to physical and mental problems. INTERPRETATION AND CONCLUSIONS: This novel inclusive bibliometric analysis can help research workers to quickly understand the potential and active researchers, landmark studies, and topics within their interests. We are willing to provide more beneficial data to contribute valuable research of female genital plastic surgery through this study. LEVEL OF EVIDENCE III: The journal asks authors to assign a level of evidence to each article. For a complete description of Evidence-Based Medicine ratings, see the Table of Contents or the online Instructions for Authors at www.springer.com/00266 .


Assuntos
Bibliometria , Genitália Feminina , Procedimentos de Cirurgia Plástica , Humanos , Feminino , Procedimentos de Cirurgia Plástica/métodos , Genitália Feminina/cirurgia , Cirurgia Plástica/métodos , Pesquisa Biomédica , Procedimentos Cirúrgicos em Ginecologia/métodos , Bases de Dados Factuais
3.
Aesthetic Plast Surg ; 48(13): 2573-2579, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38512408

RESUMO

BACKGROUND: The objective of this study is to evaluate the legal proceedings that arise from Female Genital Cosmetic Surgeries (FGCS) and analyze the reasons why women file complaints against their surgeons. Additionally, we examined the outcomes of the legal decisions associated with these complaints. METHODS: This descriptive cross-sectional study was conducted in Tehran province, Iran, from 2012 to 2021. The primary data source for this study was forensic medical records, which were reviewed to gather relevant information. The collected data included the characteristics of the participants, the reasons for lawsuits, the procedure setting, and the outcomes of the legal decisions. RESULTS: A total of 121 patients were examined in the study, revealing that Labiaplasty was the most prevalent procedure (49.6%), followed by vaginoplasty (19.8%) and perineoplasty (13.2%). The most common complaints were related to cosmetic concerns (57%), lack of recovery (26.4%), and sexual dysfunctions (22.3%). Healthcare providers were found liable for malpractice in 52.1% of cases. Additionally, having the surgery performed by a gynecologist decreased the risk of malpractice (ß = 0.21, p= 0.034), while procedures in private clinics increased the risk (ß = 2.95, p = 0.040). CONCLUSION: The study's findings emphasized the importance of providing women with comprehensive education and consultations to ensure they are well-informed about the potential outcomes and risks of FGCS. Furthermore, the study highlighted the significance of having these surgical procedures performed by skilled and experienced surgeons. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Imperícia , Humanos , Feminino , Irã (Geográfico) , Estudos Transversais , Adulto , Imperícia/legislação & jurisprudência , Imperícia/estatística & dados numéricos , Adulto Jovem , Procedimentos de Cirurgia Plástica/legislação & jurisprudência , Pessoa de Meia-Idade , Procedimentos Cirúrgicos em Ginecologia/legislação & jurisprudência , Cirurgia Plástica/legislação & jurisprudência , Genitália Feminina/cirurgia , Adolescente
4.
Aesthetic Plast Surg ; 48(13): 2459-2464, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38472349

RESUMO

BACKGROUND: This study aims to document a woman's external genitalia data in the form of a labiogram and investigate whether variations in the size of specific components of a woman's external genitalia can influence her overall satisfaction with the esthetic appearance of her genitalia. METHODS: A cross-sectional observational study was carried out on a sample of 500 Iranian women. Socio-demographic information was collected for all participants, and they completed the Female Genital Self-Image Scale (FGSIS) questionnaire. Measurements of different external genitalia components were obtained for all participants. RESULTS: The findings revealed that there was no significant association between the measurements of the external genitalia and age or BMI. However, a significant negative correlation was observed between the total score on the FGSIS and specific parameters related to the width of different sections of the labia minora. The correlations were as follows: left lower third (r = - 0.305), lower right third (r = - 0.302), left middle third (r = - 0.365), right middle third (r = - 0.435), left upper third (r = - 0.397), and right upper third (r = - 0.407) (P value< 0.001). Moreover, cutoff points of 1.95 cm on the left side and 1.90 cm on the right side were identified through analysis as thresholds for predicting dissatisfaction among women. CONCLUSION: This study suggests that the width of the labia minora might influence certain women's motivation to undergo labiaplasty, a surgical procedure designed to modify the labia minora. To help women make informed decisions, it is crucial for those considering the procedure to have a comprehensive understanding of different labia minora types, potential benefits, and associated risks. By being well-informed, individuals can make choices that align with their personal preferences and priorities. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Genitália Feminina , Satisfação do Paciente , Humanos , Feminino , Irã (Geográfico) , Estudos Transversais , Adulto , Adulto Jovem , Satisfação do Paciente/estatística & dados numéricos , Genitália Feminina/anatomia & histologia , Genitália Feminina/cirurgia , Pessoa de Meia-Idade , Vulva/cirurgia , Vulva/anatomia & histologia , Autoimagem , Imagem Corporal/psicologia , Satisfação Pessoal , Adolescente , Inquéritos e Questionários , Estética
5.
Zhonghua Fu Chan Ke Za Zhi ; 59(5): 360-367, 2024 May 25.
Artigo em Zh | MEDLINE | ID: mdl-38797565

RESUMO

Objective: To explore the age of onset and consultation, the main clinical manifestations, common types of combined malformations, the relationship of endometriosis, surgical prognosis and different types of proportion of adolescent female reproductive system dysplasia. Methods: The medical records of 356 patients (aged 10-19) with female reproductive system dysplasia in Women's Hospital, School of Medicine, Zhejiang University from January 2003 to August 2018 were collected and retrospectively analyzed. Results: (1) Among the 356 adolescent dysplasia patients, uterine dysplasia (23.6%, 84/356), oblique vaginal septum syndrome (OVSS; 22.5%, 80/356) and vaginal dysplasia (21.6%, 77/356) were the most frequent ones, followed by multi-sectional dysplasia (16.0%, 57/356), other types of developmental abnormalities like external genitaliaand urogenital fistula (13.5%, 48/356) and Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome; 2.8%, 10/356). (2) There were significant differences between the median age of onset and the age of consultation of patients with OVSS and other types of abnormalities except hymen atresia (both P<0.05). In contrast, there were no significant differences between the age of onset and the age of consultation of the patients of uterine dysplasia, vaginal dysplasia, hymen atresia, MRKH syndrome and multi-sectional dysplasia (all P>0.05). (3) The clinical manifestations were lack of specificity, and mainly abnormal finding was lower abdominal pain. (4) After admission, the majority of patients underwent comprehensive cardiopulmonary examination (71.3%, 254/356) and urinary system examination (63.5%, 226/356). Only 18.3% (65/356) of patients had completed abdominal organ examination, and 5.9% (21/356) skeletal system examination. About other systemic malformations, urological malformations were the most common (27.5%, 98/356), followed by anorectal malformation (0.6%, 2/356), heart malformations (0.3%, 1/356), and spinal malformations (0.3%, 1/356). 46.4% (84/181) of the surgical patients were diagnosed with combined endometriosis. Patients with obstructive genital tract malformations were more likely to combine with endometriosis than non-obstructive ones [50.3% (74/147) vs 29.4% (10/34); P<0.05]. However, there was no significant difference between the severity of endometriosis of those two kinds (P>0.05). (5) Totally 308 patients were followed up successfully with a median of 25.0 years old, and 20 cases were treated again; 12.0% (37/308) of them were suffering from menstrual disorder and 33.1% (102/308) of them with dysmenorrhea. Totally 130 patients had sexually active reported no sexual problems. Conclusions: Uterine dysplasia, OVSS and vaginal dysplasia are the most common syndromes in adolescent female reproductive system dysplasia along with frequent cases of coexisting urinary malformations and increasing risks of endometriosis. Meanwhile, the lack of specificity of clinical manifestations might delay the timely diagnosis and treatment after the onset of symptoms. Nonetheless, most patients could achieve good surgical outcomes.


Assuntos
Transtornos 46, XX do Desenvolvimento Sexual , Anormalidades Congênitas , Endometriose , Ductos Paramesonéfricos , Útero , Vagina , Humanos , Feminino , Adolescente , Estudos Retrospectivos , Vagina/anormalidades , Vagina/cirurgia , Ductos Paramesonéfricos/anormalidades , Endometriose/cirurgia , Endometriose/diagnóstico , Endometriose/patologia , Transtornos 46, XX do Desenvolvimento Sexual/cirurgia , Anormalidades Congênitas/epidemiologia , Útero/anormalidades , Útero/cirurgia , Útero/patologia , Adulto Jovem , Anormalidades Urogenitais/cirurgia , Anormalidades Múltiplas/epidemiologia , Criança , Prognóstico , Genitália Feminina/anormalidades , Genitália Feminina/cirurgia , Genitália Feminina/patologia
6.
J Am Acad Dermatol ; 89(2): 301-308, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-36918082

RESUMO

BACKGROUND: Conventional excision of female genital skin cancers has high rates of local recurrence and morbidity. Few publications describe local recurrence rates (LRRs) and patient-reported outcomes (PROs) after Mohs micrographic surgery (MMS) for female genital skin cancers. OBJECTIVE: To evaluate LRRs, PROs, and interdisciplinary care after MMS for female genital skin cancers. METHODS: A retrospective case series was conducted of female genital skin cancers treated with MMS between 2006 and 2021 at an academic center. The primary outcome was local recurrence. Secondary outcomes were PROs and details of interdisciplinary care. RESULTS: Sixty skin cancers in 57 patients were treated with MMS. Common diagnoses included squamous cell cancer (n = 26), basal cell cancer (n = 12), and extramammary Paget disease (n = 11). Three local recurrences were detected with a mean follow-up of 61.1 months (median: 48.8 months). Thirty-one patients completed the PROs survey. Most patients were satisfied with MMS (71.0%, 22/31) and reported no urinary incontinence (93.5%, 29/31). Eight patients were sexually active at follow-up and 75.0% (6/8) experienced no sexual dysfunction. Most cases involved interdisciplinary collaboration 71.7% (43/60). LIMITATIONS: Limitations include the retrospective single-center design, heterogeneous cohort, and lack of preoperative function data. CONCLUSIONS: Incorporating MMS into interdisciplinary teams may help achieve low LRRs and satisfactory function after genital skin cancer surgery.


Assuntos
Cirurgia de Mohs , Neoplasias Cutâneas , Humanos , Feminino , Estudos Retrospectivos , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/cirurgia , Neoplasias Cutâneas/cirurgia , Genitália Feminina/cirurgia
7.
J Paediatr Child Health ; 59(1): 95-99, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36250768

RESUMO

AIM: This study aimed to understand why adolescent girls and young women (AGYW) would seek consultation with a health professional about genital appearance concerns and/or request female genital cosmetic surgery (FGCS). The information derived from these participant interviews can inform clinical practice and help clinicians better navigate consultations with young women and girls requesting FGCS. METHODS: A qualitative exploratory study was conducted using in-depth, semi-structured interviews with AGYW (n = 11) in Victoria, Australia. Participants comprised 11 AGYW who sought consultation with a health professional when aged 13-19 years for genital appearance concerns and/or requests for FGCS. Key themes were identified using a thematic analysis approach. RESULTS: Of 11 participants, five had undergone FGCS between the ages of 13 and 23 years. Key reasons for seeking a consultation identified in the interviews included: ideas about what 'normal' genitals look like, experiences of sexual harassment and bullying, and concerns about genital appearance developing before sexual debut. CONCLUSIONS: It is important to understand why AGYW want to access these procedures, given the risks involved, and that FGCS is not recommended by paediatric specialist organisations. Understanding why AGYW seek consultation for FGCS can help inform clinical practice, and the views expressed by participants in this study can help clinicians who work in this area to better support their patients.


Assuntos
Assédio Sexual , Cirurgia Plástica , Criança , Humanos , Feminino , Adolescente , Adulto Jovem , Adulto , Cirurgia Plástica/métodos , Vitória , Genitália Feminina/cirurgia , Saúde da Mulher
8.
Aesthet Surg J ; 43(10): 1161-1173, 2023 09 14.
Artigo em Inglês | MEDLINE | ID: mdl-37078824

RESUMO

Performance of female genital cosmetic and reconstructive procedures (FGCRP) has been increasing over past decades. Appearance and functional concerns are the most common reasons for seeking FGCRP. Poor body and genital self-image may contribute to the increase in demand for surgery. The aim of this systematic review is to explore outcomes of FGCRP in the domains of body and genital self-image. A systematic literature review of PubMed, Web of Science, Scopus, PsycINFO, Embase, and the Cochrane Library was conducted to identify articles that measured body and genital self-image in females after FGCRP. The authors identified 5 articles for a systematic review of body image and 8 studies for a systematic review of genital self-image. The most common procedure performed was labia minora labiaplasty. Instruments for body image evaluation were the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder and the Body Image Quality of Life Inventory. Genital image was assessed with the Female Genital Self-Image Scale and Genital Appearance Satisfaction (GAS) scale. Most of the studies indicated that FGCRP can improve both body image and genital self-image; meta-analysis revealed that FGCRP improved GAS scores by 17.96 (range: 0-33; P < .001). It appears that FGCRP leads to improvements in females' body and genital self-image. Inconsistencies in study design and measures, however, limit this conclusion. Future research should involve more rigorous study designs (for example randomized clinical trials with large sample sizes) for a more accurate assessment of FGCRP's consequences.


Assuntos
Procedimentos de Cirurgia Plástica , Qualidade de Vida , Feminino , Humanos , Autoimagem , Genitália Feminina/cirurgia , Imagem Corporal , Procedimentos de Cirurgia Plástica/efeitos adversos , Ensaios Clínicos Controlados Aleatórios como Assunto
9.
Aesthet Surg J ; 43(11): 1334-1344, 2023 10 13.
Artigo em Inglês | MEDLINE | ID: mdl-37140012

RESUMO

BACKGROUND: Standardized photographic recording and anatomic evaluation are crucial to refined and comprehensive preoperative design and enhanced aesthetic effect of female genital cosmetic surgery. OBJECTIVES: The authors aim to propose a standard photographic scheme and physical examination form for the anatomical assessment of patients undergoing female genital surgery. METHODS: The scheme containing 2 positions (standing and lithotomy positions) and 11 views (1 frontal and 2 oblique views from standing position; 6 frontal views with labia minora open and closed, pulled to the opposite side, clitoral hood pushed up, posterior fourchette stretched; 2 oblique views from lithotomy position) (2P11V) is applied to record pre- and postoperative appearance of the vulva. The evaluation form is utilized to record characteristics of different anatomical subunits during photography. RESULTS: Two hundred forty-five patients who underwent female genital surgery were enrolled in the research from October 2018 to October 2022. All the patients received preoperative and postoperative 2P11V photography with about 5-minutes' shooting time. Various anatomical variations containing hypertrophy and prolapse of mons pubis, redundant types of labia minora and clitoral hood, incremental exposure of clitoral glans, hypo- to hypertrophy of labia majora, disappearance of interlabial groove, hypertrophy of posterior fourchette, and relation of subunits were accurately documented. CONCLUSIONS: 2P11V photographic scheme displays the isolated features of each organ and proportion relation among different parts of vulva. The standard photographic record and physical examination form offer detailed anatomical structure to surgeons and facilitate surgeons to carry out an accurate surgical design, which deserve to be promoted and applied.


Assuntos
Genitália Feminina , Vulva , Humanos , Feminino , Genitália Feminina/cirurgia , Vulva/cirurgia , Clitóris/cirurgia , Hipertrofia , Fotografação
10.
J Urol ; 205(5): 1483-1489, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33347777

RESUMO

PURPOSE: We investigated quality of life, long-term lower urinary tract symptoms, sexual function and subjective attitudes toward surgery in adult women after feminizing genitoplasty for congenital adrenal hyperplasia. MATERIALS AND METHODS: We retrospectively reviewed the medical files of all patients with congenital adrenal hyperplasia who underwent feminizing genitoplasty from 1996 to 2018 in our tertiary center. Of those, patients older than 16 years of age were asked to answer 1 nonvalidated and 3 standardized and validated questionnaires evaluating their current mental well-being (WHO-5 Well-Being Index), lower urinary tract symptoms (ICIQ-FLUTS) and sexual function (GRISS). The anonymized answers of this cross-sectional study were compared to a control group of 50 healthy females. Student's t-test, Pearson's χ2 test, Fisher's exact test and Spearman's rank correlation coefficient were performed. A p-value less than 0.05 was considered significant. RESULTS: Out of 106 patients who underwent feminizing genitoplasty, 64 patients were included and 32 patients, aged 17 to 40 years (median 25.5 years), answered the questionnaires (50% response rate). The difference between congenital adrenal hyperplasia and control group mental well-being was not statistically significant (WHO-5 median score 60 and 64, respectively; p=0.82). We found no significant difference in the lower urinary tract symptoms subscales of filling, voiding or incontinence, nor in the overall lower urinary tract symptoms score (ICIQ-FLUTS overall median score 3.5 and 3, respectively; p=0.43). CONCLUSIONS: We found in our group no abnormal mental well-being or prevalence of long-term symptoms of lower urinary tract dysfunction in adult female patients with congenital adrenal hyperplasia following feminizing genitoplasty.


Assuntos
Hiperplasia Suprarrenal Congênita/cirurgia , Genitália Feminina/cirurgia , Sintomas do Trato Urinário Inferior/epidemiologia , Complicações Pós-Operatórias/epidemiologia , Cirurgia de Readequação Sexual , Adolescente , Adulto , Atitude Frente a Saúde , Estudos Transversais , Feminino , Humanos , Qualidade de Vida , Estudos Retrospectivos , Autorrelato , Cirurgia de Readequação Sexual/psicologia , Sexualidade/fisiologia , Adulto Jovem
11.
J Sex Med ; 18(12): 1945-1949, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34688584

RESUMO

There has been an increase in genital cosmentic surgeries over the past decade, with the most common procedure being labiaplasty. This trend has many origins, but a significant motivator is genital self image, which has been shown to be very culturally influenced. Furthermore genital self modification, by way of grooming also is felt to play a role in the desire to surgically alter one's genital appearance. Given the cultural aspect of these practices, sexual health proivders should be aware of the role of self image and self modification in the drive towards persuing surgical changes to the genitals. Schmidt CN, Rowen TS. Female Genital Self-Image and Modification. J Sex Med 2021;18:1945-1949.


Assuntos
Imagem Corporal , Autoimagem , Emoções , Feminino , Genitália , Genitália Feminina/cirurgia , Humanos
12.
BMC Vet Res ; 17(1): 244, 2021 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-34266445

RESUMO

BACKGROUND: The source of multipotent stromal cells (MSC) can have a significant influence on the health and expansion capacity of the cells. As the applications for allogeneic MSCs in the treatment of feline diseases increase, the location of the initial donor tissue must be analyzed. To date, comparisons have only been made between feline MSCs collected from bone marrow or abdominal fat. This is the first report to compare cells obtained from different adipose depots in the cat with a focus on clinically relevant donor tissues. The tissue was collected from 34 healthy cats undergoing spaying (fat around the ovaries and uterine horn) or subcutaneous fat collected during surgical procedures. RESULTS: The amount of starting material is essential to isolate sufficient MSCs. The total tissue yield from the subcutaneous fat was significantly greater than could be obtained from around the reproductive organs, leading to 3 times more MSCs per donor. However, the concentration of MSCs obtained from reproductive fat was higher than from subcutaneous fat. In addition, the viability of the MSCs from the reproductive fat was significantly higher than the subcutaneous fat. Since most spaying occurs in young cats (under 18 months) reproductive fat was collected from adult cats during spaying, illustrating that age did not alter the yield or viability of the MSCs. When sufficient tissue was collected, it was digested either mechanically or enzymatically. Mechanical digestion further decreased the viability and yield of MSCs from subcutaneous fat compared to enzymatic digestion. Biomarkers of stem cell characterization, expansion capacity and function were detected using qPCR. CD70, CD90 and CD105 were all expressed in high levels in the 3 groups. However, the reproductive fat had higher levels of CD73 with the mechanically digested subcutaneous fat having the least. Gata6 was detected in all samples while Sox2 and Sox17 were also detected with higher quantities found in the enzymatically digested subcutaneous fat. Negative control genes of Gata4 and Pdx1 showed no detection prior to 50 cycles. During the first three passages, age of the donor, location of the donor tissue, or digestion protocol had no effect on cell culture doubling times or cell viability. CONCLUSIONS: While MSCs from reproductive fat had superior cells/tissue weight and initial viability, there were still dramatically fewer cells obtained compared to subcutaneous fat due to the limited amount of tissue surrounding the reproductive organs. Further, in P1-P3 cultures there were no differences noted in doubling time or cell viability between tissue obtained from reproductive or subcutaneous fat depots.


Assuntos
Gatos , Gordura Intra-Abdominal/citologia , Células-Tronco Mesenquimais/citologia , Gordura Subcutânea/citologia , Animais , Técnicas de Cultura de Células/métodos , Técnicas de Cultura de Células/veterinária , Diferenciação Celular , Proliferação de Células , Sobrevivência Celular , Feminino , Genitália Feminina/cirurgia , Masculino , Células-Tronco Mesenquimais/fisiologia
13.
Anaesthesia ; 76 Suppl 4: 39-45, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-33682101

RESUMO

Adolescents represent a quarter of the world's population, yet their specific healthcare needs have often not been acknowledged. Whilst many operations in this population will be performed in specialist tertiary centres and children's hospitals, it is likely that care will be sought in a variety of healthcare settings, and so it is important to have an understanding of the particular approach to this age group. Paediatric and adolescent gynaecology emerged as a speciality in 2000 with the inauguration of the British Society for Paediatric and Adolescent Gynaecology, a specialist society of the Royal College of Obstetricians and Gynaecologists. This is a multidisciplinary group, comprising paediatricians, paediatric surgeons, psychologists and nurses, although the majority of the members are gynaecologists. In this review, we will describe the peri-operative implications of adolescent gynaecological surgery and the considerations that need to be applied to this specific age group, such as consent, the operative setting and key personnel. We will also discuss specialist situations which are likely to fall to an adolescent gynaecology setting, such as management of those with Mullerian abnormalities, which often present with pelvic pain in adolescence. We discuss those with a history of ritual female genital cutting (female genital mutilation), trans men and those with significant learning difficulties. In all circumstances, teamwork, reflection and pragmatism are key.


Assuntos
Anestésicos/administração & dosagem , Ductos Paramesonéfricos/cirurgia , Adolescente , Feminino , Genitália Feminina/cirurgia , Humanos , Laparoscopia , Ductos Paramesonéfricos/anormalidades , Assistência Perioperatória , Pessoas Transgênero
14.
Aust N Z J Obstet Gynaecol ; 61(3): 331-338, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33382090

RESUMO

BACKGROUND: Despite increasing numbers of labiaplasties being performed, there is little quantitative information on normal labial diversity to guide medical education, patient education and surgical treatment. AIM: This scoping review will determine what is known in the published literature about the anatomical basis of normal for labia and female genital cosmetic surgery (FCGS). MATERIALS AND METHODS: The scoping review identified ten population-based studies that recorded labial dimensions by searching three electronic databases utilising a Preferred Reporting Items for Systematic Reviews and Meta-Analyses search strategy. Strict inclusion and exclusion criteria were applied and then reference lists were scrutinised until no further articles that met the criteria were located. RESULTS: These studies showed significant variation in labial length (range 5-100 mm) and width (range 1-60 mm). Labia minora were wider in pre-menopausal women than in post-menopausal women, protruding labia minora were more common than not, and asymmetry between right and left labia was common. Variation in recruitment, inclusion and exclusion criteria, and measurement did not allow for summation of the data sets. CONCLUSION: This information could usefully be added to medical textbooks and teaching to ensure that medical graduates are sufficiently informed about normal variation in female genital anatomy to assess and advise women seeking FGCS.


Assuntos
Procedimentos de Cirurgia Plástica , Vulva , Feminino , Genitália Feminina/cirurgia , Procedimentos Cirúrgicos em Ginecologia , Humanos , Vulva/cirurgia
15.
Clin Anat ; 34(3): 420-430, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32783342

RESUMO

INTRODUCTION: Congenital variations of the reproductive system arise during embryonal organogenesis, although their clinical manifestations present later in adolescence or during reproductive years due to functional disorders such as abnormal menstruation, sexual dysfunction, infertility, and pregnancy loss. Surgical treatment of congenital variations is performed according to variant anatomy and functional disorders. However, many congenital anatomic variations are difficult to categorize based on current classification systems. The aim of this study is to distinguish female genital anatomic variations for appropriate surgical treatment based on a clinical analysis of uterovaginal malformations and disorders of sex development. The deviant anatomy defined as variations, which has been used in the manuscript instead of anomalies. MATERIALS AND METHODS: A retrospective review was conducted of 718 cases of uterovaginal malformation and 144 cases with disorders of sex development. Physical variations were assessed by ultrasound, magnetic resonance imaging, and laparoscopy. Genetic studies were conducted for individuals with disorders of sex development. Classification of variants was determined by physical findings, genetic findings, and clinical presentations. RESULTS: A unified systematization for female genital anatomic variations was proposed, based on the genome (karyotype), gonadal morphology, internal and external genital anatomy. The internal anatomy was classified to uterovaginal variations, which have distinguished to 11 basic types and 24 variants, according to morphologic patterns. Surgical treatments are proposed based on these variants. CONCLUSION: These new classifications provide a framework for clinical management and appropriate surgical treatment of female genital anatomic variants, with the aim of improving reproductive outcomes.


Assuntos
Genitália Feminina/anormalidades , Genitália Feminina/diagnóstico por imagem , Feminino , Genitália Feminina/cirurgia , Humanos , Estudos Retrospectivos
16.
Int Braz J Urol ; 47(4): 861-867, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33848081

RESUMO

INTRODUCTION: 46,XX Congenital adrenal hyperplasia (CAH) remains the first cause of genital virilization and current surgical techniques aim to restore female aspect of genitalia while preserving dorsal neurovascular bundle but not at the expense of not preserving erectile tissue. We aim to report our experience with a new surgical technique for clitoroplasty, completely preserving corporeal bodies, neurovascular bundles without dismembering the clitoris, in four patients with over a year follow up. MATERIALS AND METHODS: After IRB approval four patients with 46,XX CAH and Prader 5 and 3 external genitalia, underwent feminizing genitoplasty. Complete preservation of erectile tissue was accomplished without a need to dissect dorsal neurovascular bundle. Glans size allowed no need for glanular reduction and there was no need to dismember the corporeal bodies. RESULTS: Four patients 12 to 24-months-old underwent complete corporeal preservation clitoroplasty (CCPC), mean age was 18.5 months, mean follow up was 10.25 months. Vaginoplasty was performed in all patients with partial urogenital mobilization (PUM) and Urogenital Sinus flap (UF), only one severely virilized patient required a parasagittal pre-rectal approach to mobilize the vagina. We had no complications until last follow up. CONCLUSION: To our knowledge, we are introducing the concept of CCPC without the need of disassembling the corporeal bodies, neurovascular bundle and glans. It stands as a new alternative for feminizing genitoplasty with complete preservation of erectile tissue and no dissection of neurovascular bundle. Although there is still lacking long-term follow-up, it represents a new step in conservative reconfiguration of the external virilized female genitalia.


Assuntos
Hiperplasia Suprarrenal Congênita , Procedimentos de Cirurgia Plástica , Adolescente , Hiperplasia Suprarrenal Congênita/cirurgia , Pré-Escolar , Clitóris/cirurgia , Feminino , Genitália Feminina/cirurgia , Humanos , Lactente , Masculino , Retalhos Cirúrgicos , Vagina/cirurgia
17.
Aesthet Surg J ; 41(12): 1400-1408, 2021 11 12.
Artigo em Inglês | MEDLINE | ID: mdl-33843969

RESUMO

BACKGROUND: Transcutaneous temperature-controlled radiofrequency (TTCRF) treatment is an emerging modality for vulvovaginal rejuvenation. However, clinical experience with this modality is limited. OBJECTIVES: The aim of this study was to examine the efficacy of TTCRF treatment in improving female genital appearance, sexual function, and stress urinary incontinence (SUI). METHODS: Forty-eight patients complaining of sexual dysfunction (SD; n = 41) and/or SUI (n = 37) were included. Most patients had ≤3 TTCRF sessions. To evaluate the aesthetic results, photographs of the genital area taken before treatment were compared to those taken 6 weeks posttreatment in a blinded manner. Prior to treatment and 6 weeks after the final session, the Female Sexual Function Index (FSFI) questionnaire was administered to participants complaining of SD and the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-UI-SF) to those with complaints/symptoms of SUI. Preprocedure scores were compared with postprocedure scores by paired t test. RESULTS: Aesthetic improvement was noted in all patients. Preprocedure mean total FSFI score was 21.77 vs the respective postprocedure score of 25.79 (P < 0.00001). Most FSFI domains improved (pre- vs post-TTCRF mean score): sexual desire (from 2.99 to 3.54), arousal (from 3.14 to 3.83), orgasm (from 3.14 to 4.39), pain (from 4.41 to 5.04) (P < 0.00001 for all) and satisfaction (from 3.75 to 4.42; P = 0.001). Mean preprocedure ICIQ-UI-SF score was 10.10 and decreased to 4.81 (P < 0.00001) postprocedure. CONCLUSIONS: A substantial improvement in genital appearance was observed. Assessment based on validated instruments demonstrated significant improvements in sexual function and SUI. TTCRF is a safe and effective treatment for these conditions.


Assuntos
Disfunções Sexuais Fisiológicas , Incontinência Urinária por Estresse , Feminino , Genitália Feminina/cirurgia , Humanos , Disfunções Sexuais Fisiológicas/diagnóstico , Disfunções Sexuais Fisiológicas/etiologia , Disfunções Sexuais Fisiológicas/terapia , Inquéritos e Questionários , Temperatura , Resultado do Tratamento , Incontinência Urinária por Estresse/cirurgia
18.
Wiad Lek ; 73(12 cz 2): 2909-2914, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33611302

RESUMO

OBJECTIVE: The aim: To identify problems associated with non-medical genital surgery and establish the limits of acceptable medical intervention in such operations. PATIENTS AND METHODS: Materials and methods: The study is based on a theoretical basis, which includes reviews of legislation, reports from non-governmental organizations, and is based on empirical data: decisions of the European Court of Human Rights, international regulations, statistics of the World Health Organization. Systemic and structural, comparative legal and functional methods, systematization, analysis and synthesis were decisive in the research process. CONCLUSION: Conclusions: "Female genital mutilation" or "female circumcision" is essentially a separate type of bodily injury that is caused intentionally in accordance with various social domestic and religious traditions and beliefs of certain emigrant ethnical religious communities. Such actions are a form of discrimination and violation of women's rights on the basis of gender, as well as a form of child abuse, as the vast majority of such operations are carried out on girls under 12 years of age. Medical intervention in case of operations on female genitalia, including for non-therapeutic purposes, can be considered legitimate only with the informed consent of the patient and on conditions that the level of danger to human health from such intervention corresponds to the concept of personal autonomy, that is, it does not require direct state intervention for the reasons of urgent social necessity.


Assuntos
Circuncisão Feminina , Emigrantes e Imigrantes , Criança , Feminino , Genitália Feminina/cirurgia , Humanos , Consentimento Livre e Esclarecido , Masculino , Autonomia Pessoal
19.
J Obstet Gynaecol Res ; 45(7): 1382-1385, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30993814

RESUMO

Synchronous mucinous metaplasia and neoplasms of the female genital tract (SMMN-FGT) is a rare disease reported by a few scholars without the consensus of diagnosis and treatment. Here we will report a 57-year-old female patient from Zhejiang China who suffered from this disease. She came to our hospital because of a large amount of vaginal discharge. All the medical examination was negative except hydrometra, and the left fallopian tube was segmenting and thickening. Then she had a total hysterectomy and a bilateral salpingo-oophorectomy and was finally diagnosed with pathological evidence. In addition, the positron emission tomography-computed tomography scan after the operation revealed no residual tumors, and the case needed further follow-up.


Assuntos
Neoplasias das Tubas Uterinas/patologia , Neoplasias dos Genitais Femininos/patologia , Genitália Feminina/patologia , Neoplasias Císticas, Mucinosas e Serosas/patologia , Neoplasias Primárias Múltiplas/patologia , China , Neoplasias das Tubas Uterinas/cirurgia , Feminino , Neoplasias dos Genitais Femininos/cirurgia , Genitália Feminina/cirurgia , Humanos , Metaplasia , Pessoa de Meia-Idade , Neoplasias Císticas, Mucinosas e Serosas/cirurgia , Neoplasias Primárias Múltiplas/cirurgia
20.
Aesthetic Plast Surg ; 43(4): 1102-1110, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31087118

RESUMO

BACKGROUND: Patient demand for aesthetic genital surgery has markedly increased. The International Society of Aesthetic Plastic Surgery reported 95,010 labiaplasties and 50,086 vaginal rejuvenation procedures in 2015. METHODS: We performed an online anonymous survey to evaluate the teaching of female genital procedures in plastic surgery training programs worldwide. RESULTS: A total of 1033 board certified plastic surgeons answered the survey. Most respondents were from the USA, Brazil, Mexico and Colombia. The majority of plastic surgeons performing these procedures were in private practice (77.62%) and (22.38%) in academic settings. Most plastic surgeons (75.63%) did not receive formal education in female genital rejuvenation procedures however 54.31% did receive education in reconstruction procedures. During their training, most were exposed to vaginal reconstruction (15.94%), labia minora reduction (11.9%), vulva reconstruction (11.53%), flaps for vaginal agenesis (11.39%) and monsplasty (7.98%). Additional training for female genital procedures was mostly at meetings and shadowing experts. Sixty-two percent reported that patients seldom requested those procedures, and 63.73% reported these procedures comprised less than 5% of their practice. The most commonly performed procedures were labia minora reduction, labia majora augmentation or reduction and monsplasty. The materials used were mostly fat grafting, hyaluronic acid injections and lasers. CONCLUSION: Additional formal training during residency for aesthetic genital surgery would be beneficial. Additionally, courses at meetings would be useful for plastic surgeons who have had insufficient training. More studies need to be conducted on the different female genital rejuvenation procedures offered in order to evaluate patients' long-term outcomes and satisfaction. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Educação de Pós-Graduação em Medicina/métodos , Genitália Feminina/cirurgia , Satisfação do Paciente/estatística & dados numéricos , Procedimentos de Cirurgia Plástica/educação , Cirurgia Plástica/educação , Brasil , Competência Clínica , Feminino , Procedimentos Cirúrgicos em Ginecologia/educação , Procedimentos Cirúrgicos em Ginecologia/métodos , Humanos , México , Procedimentos de Cirurgia Plástica/métodos , Estudos Retrospectivos , Medição de Risco , Inquéritos e Questionários
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