DGAT1 K232A polymorphism in Brazilian cattle breeds
Genet. mol. res. (Online)
; 5(3): 475-482, 2006. ilus, tab
Article
em En
| LILACS
| ID: lil-441042
Biblioteca responsável:
BR1.1
ABSTRACT
Recent reports identified DGAT1 (EC 2.3.1.20) harboring a lysine to alanine substitution (K232A) as a candidate gene with a strong effect on milk production traits. Our objective was to estimate the frequency of the DGAT1 K232A polymorphism in the main Zebu and Taurine breeds in Brazil as well as in Zebu x Taurine crossbreds as a potential QTL for marker-assisted selection. Samples of 331 animals from the main Brazilian breeds, Nellore, Guzerat, Red Sindhi, Gyr, Holstein, and Gyr x Holstein F1 were genotyped for DGAT1 K232A polymorphism (A and K alleles) using the PCR-RFLP technique. The highest frequency of the A allele was found in the Holstein sample (73%) followed by Gyr x Holstein F1 (39%). Gyr and Red Sindhi showed low frequencies of A alleles (4 and 2.5%, respectively). The A allele was not found in the Nellore and Guzerat samples. Our results could be used to guide association studies between this locus and milk traits in these breeds.
Palavras-chave
Texto completo:
1
Base de dados:
LILACS
Assunto principal:
Polimorfismo Genético
/
Bovinos
/
Locos de Características Quantitativas
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Leite
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Diacilglicerol O-Aciltransferase
País/Região como assunto:
America do sul
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Brasil
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Brasil