Comparison of a 2.5% and a 4.25% dextrose peritoneal equilibration test.
Perit Dial Int
; 22(3): 365-70, 2002.
Article
em En
| MEDLINE
| ID: mdl-12227395
ABSTRACT
BACKGROUND:
Ultrafiltration (UF) failure develops over time in some patients on peritoneal dialysis. The workup of UF failure can be difficult and the 4.25% peritoneal equilibration test (PET) has been suggested to be more useful than the 2.5% PET for the workup of UF failure. It is unknown how a 4.25% PET compares to a 2.5% PET in individual patients.OBJECTIVES:
To assess the differences in drain volumes and sodium sieving using a 4.25% PET compared to a 2.5% PET, and to determine whether peritoneal transport rates, in terms of dialysate-to-plasma (D/P) ratios, are comparable between the two.DESIGN:
Pilot study with each patient serving as his or her own control.SETTING:
Outpatient dialysis facility of Wake Forest University Baptist Medical Center. PATIENTS 47 patients, all of whom had a 2.5% PET and a 4.25% PET performed within 1 week of each other. OUTCOMEMEASURES:
Dialysate-to-plasma ratios of urea and creatinine, dialysate total protein, and dialysate glucose compared to time zero (D/D0) at 0, 2, and 4 hours. Four-hour drain volumes and sodium sieving at 2 hours were also measured.RESULTS:
There was reproducibility between the 2.5% and 4.25% PET for D/P ratios of urea and creatinine and for dialysate total protein. There were expected differences in drain volume, sodium sieving, and D/D0 glucose between the two methods.CONCLUSIONS:
The use of a 4.25% PET may be more useful for the workup of UF failure because of the accentuation of drain volume and sodium sieving, while remaining useful for prescription management.
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Base de dados:
MEDLINE
Assunto principal:
Peritônio
/
Desequilíbrio Hidroeletrolítico
/
Transporte Biológico Ativo
/
Hemofiltração
/
Glucose
/
Falência Renal Crônica
Idioma:
En
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos