Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands.
Bioorg Med Chem Lett
; 16(6): 1549-52, 2006 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-16386422
We report the discovery of a novel class of glucocorticoid receptor (GR) ligands based on 1,2-dihydroquinoline molecular scaffold. The compounds exhibit good GR binding affinity and selectivity profile against other nuclear hormone receptors.
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Base de dados:
MEDLINE
Assunto principal:
Quinolinas
/
Receptores de Glucocorticoides
Idioma:
En
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Estados Unidos