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A case of cholesterol embolism confirmed by skin biopsy and successfully treated with statins and steroids.
Matsumura, Takayoshi; Matsumoto, Akihiro; Ohno, Minoru; Suzuki, Shinya; Ohta, Miki; Suzuki, Etsu; Takenaka, Katsu; Hirata, Yasunobu; Fujita, Toshiro; Nagai, Ryozo.
Afiliação
  • Matsumura T; Department of Cardiovascular Medicine, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Am J Med Sci ; 331(5): 280-3, 2006 May.
Article em En | MEDLINE | ID: mdl-16702800
ABSTRACT
Although cholesterol embolism syndrome was recognized as a clinicopathologic entity more than 50 years ago, it is attracting growing attention recently. It is a multisystemic disorder in which cholesterol crystals released from atherosclerotic plaques obstruct small arterioles, resulting in local ischemia and end-organ damage. There are no established treatments, and with the limited treatment options available, it is important to make the diagnosis as early as possible. We present the case of a 68-year-old man with cholesterol embolism who had a few fluttering atheromas in the aorta, as demonstrated by transesophageal ultrasonography. The diagnosis was confirmed by skin biopsy, and treatment with statins and steroids proved effective, as renal failure progressively improved. This case emphasizes the importance of early diagnosis and shows the possible therapeutic effects of statins and steroids for patients with this syndrome.
Assuntos
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Base de dados: MEDLINE Assunto principal: Esteroides / Dermatopatias Vasculares / Embolia de Colesterol / Inibidores de Hidroximetilglutaril-CoA Redutases Idioma: En Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Japão
Buscar no Google
Base de dados: MEDLINE Assunto principal: Esteroides / Dermatopatias Vasculares / Embolia de Colesterol / Inibidores de Hidroximetilglutaril-CoA Redutases Idioma: En Ano de publicação: 2006 Tipo de documento: Article País de afiliação: Japão