Clear cell papulosis in Hispanic siblings.
Arch Dermatol
; 143(3): 358-60, 2007 Mar.
Article
em En
| MEDLINE
| ID: mdl-17372100
ABSTRACT
BACKGROUND:
Clear cell papulosis is a rare condition that has been reported in 14 children, all but 1 of whom are of Asian descent. It was first described in 1987 and is thus named because of the presence of clear cells in the epidermis. OBSERVATION We describe the cases of 3 Hispanic children in the United States with clear cell papulosis. All 3 patients presented with multiple grouped, oval, hypopigmented macules and flat papules in the suprapubic area and trunk. Histopathologic examination revealed characteristic clear cells within the basal layer and Malpighian layer.CONCLUSIONS:
Clear cell papulosis is a unique entity with most cases reported in patients of Asian heritage. The characteristic cells have histologic and immunohistochemical similarities to Paget cells and Toker clear cells of the nipple, although the exact relationship to these cells is not clear. The natural history of clear cell papulosis is unknown; thus, continual surveillance for development of extramammary Paget disease is suggested.
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Base de dados:
MEDLINE
Assunto principal:
Hispânico ou Latino
/
Dermatopatias Papuloescamosas
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos