[Predictive value of differential pulse pressure in the diagnosis of silent myocardial ischemia in patients with type-2 diabetes]. / Valor predictivo de la presión diferencial del pulso en el diagnóstico de isquemia miocárdica silente en pacientes con diabetes tipo 2.
Rev Esp Cardiol
; 60(5): 543-7, 2007 May.
Article
em Es
| MEDLINE
| ID: mdl-17535767
ABSTRACT
Silent myocardial ischemia occurs more frequently in diabetics. Differential arterial pulse pressure is a valuable predictor of cardiovascular disease. We studied 48 consecutive male patients with type-2 diabetes and no known history of ischemic heart disease. Ambulatory monitoring of arterial pressure was carried out and the presence of silent myocardial ischemia was studied using a protocol that involved resting ECG, echocardiography, 24-hour Holter ECG, conventional exercise stress testing, and exercise testing with nuclear scanning. Nine patients (19%) had silent myocardial ischemia. Differential pulse pressure had good discriminative ability in identifying the presence of silent ischemia the area under the receiver operating characteristic (ROC) curve was 0.83 (95% confidence interval [CI], 0.71-0.96; P=.002). This predictive ability was also observed on adjusted logistic regression modeling (odds ratio [OR], 1.24, 95% CI = 1.02-1.49). We found that the OR for the risk of silent ischemia for every 10-mmHg increase in differential pulse pressure was 8.5 (95% CI 1.7-31.2). Age and differential pulse pressure were the only independent predictors of silent myocardial ischemia found in this study.
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Base de dados:
MEDLINE
Assunto principal:
Isquemia Miocárdica
/
Monitorização Ambulatorial da Pressão Arterial
/
Diabetes Mellitus Tipo 2
Idioma:
Es
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Espanha