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Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation.
Mao, Yifan; Shang, Yonglei; Pham, Victoria C; Ernst, James A; Lill, Jennie R; Scales, Suzie J; Zha, Jiping.
Afiliação
  • Mao Y; Department of Research Pathology, Genentech, South San Francisco, California 94080.
  • Shang Y; Department of Research Pathology, Genentech, South San Francisco, California 94080.
  • Pham VC; Department of Protein Chemistry, Genentech, South San Francisco, California 94080.
  • Ernst JA; Department of Protein Chemistry, Genentech, South San Francisco, California 94080.
  • Lill JR; Department of Protein Chemistry, Genentech, South San Francisco, California 94080.
  • Scales SJ; Department of Molecular Biology, Genentech, South San Francisco, California 94080. Electronic address: sscales@gene.com.
  • Zha J; Department of Research Pathology, Genentech, South San Francisco, California 94080. Electronic address: jzha@crownbio.com.
J Biol Chem ; 286(48): 41852-41861, 2011 Dec 02.
Article em En | MEDLINE | ID: mdl-21994939
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Receptor IGF Tipo 1 / Anticorpos Monoclonais Murinos / Capeamento Imunológico Idioma: En Ano de publicação: 2011 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Receptor IGF Tipo 1 / Anticorpos Monoclonais Murinos / Capeamento Imunológico Idioma: En Ano de publicação: 2011 Tipo de documento: Article