New insights into bacterial adaptation through in vivo and in silico experimental evolution.
Nat Rev Microbiol
; 10(5): 352-65, 2012 Mar 27.
Article
em En
| MEDLINE
| ID: mdl-22450379
ABSTRACT
Microbiology research has recently undergone major developments that have led to great progress towards obtaining an integrated view of microbial cell function. Microbial genetics, high-throughput technologies and systems biology have all provided an improved understanding of the structure and function of bacterial genomes and cellular networks. However, integrated evolutionary perspectives are needed to relate the dynamics of adaptive changes to the phenotypic and genotypic landscapes of living organisms. Here, we review evolution experiments, carried out both in vivo with microorganisms and in silico with artificial organisms, that have provided insights into bacterial adaptation and emphasize the potential of bacterial regulatory networks to evolve.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bactérias
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Adaptação Biológica
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Fenômenos Fisiológicos Bacterianos
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Evolução Biológica
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
França