[Risk factors and clinical outcome of coronary artery aneurysms developed after drug-eluting stent implantation].
Zhonghua Xin Xue Guan Bing Za Zhi
; 41(2): 103-7, 2013 Feb.
Article
em Zh
| MEDLINE
| ID: mdl-23710738
ABSTRACT
OBJECTIVE:
To evaluate risk factors and clinical outcome of coronary artery aneurysms (CAA) developed after drug-eluting stent implantation evidenced by coronary angiographic follow-up.METHODS:
This study analyzed 4500 consecutive patient with de novo coronary artery stenosis receiving drug-eluting stent (DES) implantation from January 2004 to May 2009. Seven hundred and sixty patients with angiographic follow-ups at 6 - 8 months and 28 - 48 months after the index procedure were enrolled. CAA was defined as a localized dilatation exceeding 1.5 times the diameter of the adjacent artery. The independent risk factors and major adverse cardiac events (MACE) including cardiac death, myocardial infarction, target-vessel revascularization (TVR) and in-stent thrombosis were analyzed.RESULTS:
CAA was detected in 70 patients with 70 lesions (9.2%, 70/760). Logistic analysis showed that lesion in an infarct-related artery (OR 5.9, P < 0.01), lesion in the left anterior descending artery (OR 4.5, P < 0.01), lesion with chronic total occlusion (OR 3.4, P < 0.05), and lesion length > 33 mm (OR 2.9, P < 0.05) were independent risk factors for CAA. Follow-up duration was (1131 ± 478) days. MACE was found in 19 patients and all received TVR. There were 11 patients with myocardial infarction and 8 patients with evidence of in-stent thrombosis. Mortality was zero during follow-up.CONCLUSIONS:
The risk factors for the development of CAA after DES are lesions in an infarct-related artery, in the left anterior descending artery, with chronic total occlusion, and with lesion length > 33 mm. MACE is not uncommon in patients with CAA and long-ferm clinical follow-up is warranted for patients with CAA.
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Base de dados:
MEDLINE
Assunto principal:
Aneurisma Coronário
/
Stents Farmacológicos
Idioma:
Zh
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
China