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Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis.
van Wijk, Xander M; Thijssen, Victor L; Lawrence, Roger; van den Broek, Sebastiaan A; Dona, Margo; Naidu, Natasha; Oosterhof, Arie; van de Westerlo, Els M; Kusters, Lisanne J; Khaled, Yasmine; Jokela, Tiina A; Nowak-Sliwinska, Patrycja; Kremer, Hannie; Stringer, Sally E; Griffioen, Arjan W; van Wijk, Erwin; van Delft, Floris L; van Kuppevelt, Toin H.
Afiliação
  • van Wijk XM; Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Thijssen VL; Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
  • Lawrence R; Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California San Diego, San Diego, California.
  • van den Broek SA; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • Dona M; Department of Otorhinolaryngology, Head and Neck Surgery, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Naidu N; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • Oosterhof A; Glycotechnology Core, University of California San Diego, San Diego, California.
  • van de Westerlo EM; Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Kusters LJ; Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Khaled Y; Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Jokela TA; Department of Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • Nowak-Sliwinska P; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
  • Kremer H; Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Centre, Amsterdam, The Netherlands.
  • Stringer SE; Institute of Bio-Engineering, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
  • Griffioen AW; Department of Otorhinolaryngology, Head and Neck Surgery, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • van Wijk E; Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands.
  • van Delft FL; Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
  • van Kuppevelt TH; Cardiovascular Research Group, University of Manchester, Manchester, United Kingdom.
ACS Chem Biol ; 8(10): 2331-8, 2013 Oct 18.
Article em En | MEDLINE | ID: mdl-23972127

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uridina Difosfato N-Acetilglicosamina / Regulação da Expressão Gênica / Heparitina Sulfato / Neovascularização Patológica Idioma: En Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Uridina Difosfato N-Acetilglicosamina / Regulação da Expressão Gênica / Heparitina Sulfato / Neovascularização Patológica Idioma: En Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Holanda