Full genome sequences and preliminary molecular characterization of three tick-borne encephalitis virus strains isolated from ticks and a bank vole in Slovak Republic.
Virus Genes
; 48(1): 184-8, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24068495
ABSTRACT
The full genome sequences of three tick-borne encephalitis virus strains, two isolated from Ixodes ricinus ticks and one from the brain of a bank vole, Myodes glareolus, originating from the Slovak Republic were determined. Nucleotide sequences were found to be very similar (>99.5 % nt-identity) with only one distinct amino acid (aa) difference to each other. They all shared 30 aa-changes when compared to type strain Neudoerfl, isolated in neighboring Austria. An internal poly(A)-stretch similar to that of strain Neudoerfl was found only in TBEV strain 114 from a tick. Despite this heterogeneity in the 3'-NCR, the high level of sequence identity was striking, indicating a low rate of nucleotide substitutions of TBEV strains in Slovakia and no obvious relation to the host species.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
RNA Viral
/
Arvicolinae
/
Genoma Viral
/
Análise de Sequência de DNA
/
Ixodes
/
Vírus da Encefalite Transmitidos por Carrapatos
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Alemanha