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Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.
Schroeder, Christina I; Swedberg, Joakim E; Withka, Jane M; Rosengren, K Johan; Akcan, Muharrem; Clayton, Daniel J; Daly, Norelle L; Cheneval, Olivier; Borzilleri, Kris A; Griffor, Matt; Stock, Ingrid; Colless, Barbara; Walsh, Phillip; Sunderland, Philip; Reyes, Allan; Dullea, Robert; Ammirati, Mark; Liu, Shenping; McClure, Kim F; Tu, Meihua; Bhattacharya, Samit K; Liras, Spiros; Price, David A; Craik, David J.
Afiliação
  • Schroeder CI; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Swedberg JE; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Withka JM; Structural Biology and Biophysics, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Rosengren KJ; School of Biomedical Sciences, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Akcan M; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Clayton DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Daly NL; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Cheneval O; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Borzilleri KA; Structural Biology and Biophysics, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Griffor M; Structural Biology and Biophysics, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Stock I; PDM-NCE, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Colless B; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Walsh P; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Sunderland P; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia.
  • Reyes A; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Dullea R; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Ammirati M; Structural Biology and Biophysics, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • Liu S; Structural Biology and Biophysics, Pfizer Global Research and Development, Eastern Point Road, Groton, CT 06340, USA.
  • McClure KF; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Tu M; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Bhattacharya SK; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Liras S; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Price DA; CVMED, Pfizer Global Research and Development, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Craik DJ; Institute for Molecular Bioscience, The University of Queensland, Brisbane, 4072 QLD, Australia. Electronic address: d.craik@imb.uq.edu.au.
Chem Biol ; 21(2): 284-94, 2014 Feb 20.
Article em En | MEDLINE | ID: mdl-24440079
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Receptores de LDL / Serina Endopeptidases / Pró-Proteína Convertases Idioma: En Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Receptores de LDL / Serina Endopeptidases / Pró-Proteína Convertases Idioma: En Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália