Aspewentins A-C, norditerpenes from a cryptic pathway in an algicolous strain of Aspergillus wentii.
J Nat Prod
; 77(2): 429-32, 2014 Feb 28.
Article
em En
| MEDLINE
| ID: mdl-24499164
ABSTRACT
Through addition of suberoylanilide hydroxamic acid, two new aromatic norditerpenes, aspewentins A (1) and B (2), along with an oxygenated derivative, aspewentin C (3), were obtained from the culture of an Aspergillus wentii strain (na-3) isolated from the tissue of the brown alga Sargassum fusiforme. The structures and absolute configurations were unambiguously elucidated by spectroscopic analyses and quantum chemical calculations. Aspewentins A-C were produced before sporulation and exhibited potent bioactivities against some marine-derived organisms.
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1
Base de dados:
MEDLINE
Assunto principal:
Aspergillus
/
Diterpenos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article