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Genome-wide association study reveals two new risk loci for bipolar disorder.
Mühleisen, Thomas W; Leber, Markus; Schulze, Thomas G; Strohmaier, Jana; Degenhardt, Franziska; Treutlein, Jens; Mattheisen, Manuel; Forstner, Andreas J; Schumacher, Johannes; Breuer, René; Meier, Sandra; Herms, Stefan; Hoffmann, Per; Lacour, André; Witt, Stephanie H; Reif, Andreas; Müller-Myhsok, Bertram; Lucae, Susanne; Maier, Wolfgang; Schwarz, Markus; Vedder, Helmut; Kammerer-Ciernioch, Jutta; Pfennig, Andrea; Bauer, Michael; Hautzinger, Martin; Moebus, Susanne; Priebe, Lutz; Czerski, Piotr M; Hauser, Joanna; Lissowska, Jolanta; Szeszenia-Dabrowska, Neonila; Brennan, Paul; McKay, James D; Wright, Adam; Mitchell, Philip B; Fullerton, Janice M; Schofield, Peter R; Montgomery, Grant W; Medland, Sarah E; Gordon, Scott D; Martin, Nicholas G; Krasnow, Valery; Chuchalin, Alexander; Babadjanova, Gulja; Pantelejeva, Galina; Abramova, Lilia I; Tiganov, Alexander S; Polonikov, Alexey; Khusnutdinova, Elza; Alda, Martin.
Afiliação
  • Mühleisen TW; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany [3] Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, D-52425 Jülich, Germany [4].
  • Leber M; 1] Institute for Medical Biometry, Informatics, and Epidemiology, University of Bonn, D-53127 Bonn, Germany [2] German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, D-53175 Bonn, Germany [3].
  • Schulze TG; 1] Department of Psychiatry and Psychotherapy, University of Go¨ttingen, D-37075 Göttingen, Germany [2].
  • Strohmaier J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, D-68159 Mannheim, Germany.
  • Degenhardt F; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany.
  • Treutlein J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, D-68159 Mannheim, Germany.
  • Mattheisen M; 1] Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark [2] Institute for Genomic Mathematics, University of Bonn, D-53127 Bonn, Germany.
  • Forstner AJ; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany.
  • Schumacher J; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany.
  • Breuer R; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, D-68159 Mannheim, Germany.
  • Meier S; 1] Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, D-68159 Mannheim, Germany [2].
  • Herms S; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany [3] Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel CH-4012, Switzerland.
  • Hoffmann P; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany [3] Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, D-52425 Jülich, Germany [4] Division of Medical Genetic
  • Lacour A; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, D-53175 Bonn, Germany.
  • Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, D-68159 Mannheim, Germany.
  • Reif A; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Würzburg, D-97070 Würzburg, Germany.
  • Müller-Myhsok B; 1] Statistical Genetics, Department of Translational Psychiatry, Max Planck Institute of Psychiatry, D-80804 Munich, Germany [2] Munich Cluster for Systems Neurology (SyNergy), D-80336 Munich, Germany [3] Institute of Translational Medicine, University of Liverpool, L69 3BX Liverpool, UK.
  • Lucae S; Statistical Genetics, Department of Translational Psychiatry, Max Planck Institute of Psychiatry, D-80804 Munich, Germany.
  • Maier W; Department of Psychiatry, University of Bonn, D-53127 Bonn, Germany.
  • Schwarz M; Psychiatric Center Nordbaden, D-69168 Wiesloch, Germany.
  • Vedder H; Psychiatric Center Nordbaden, D-69168 Wiesloch, Germany.
  • Kammerer-Ciernioch J; Psychiatric Center Nordbaden, D-69168 Wiesloch, Germany.
  • Pfennig A; Department of Psychiatry and Psychotherapy, University Hospital, D-01307 Dresden, Germany.
  • Bauer M; Department of Psychiatry and Psychotherapy, University Hospital, D-01307 Dresden, Germany.
  • Hautzinger M; Department of Psychology, Clinical Psychology and Psychotherapy, Eberhard Karls University Tübingen, D-72074 Tübingen, Germany.
  • Moebus S; Institute of Medical Informatics, Biometry, and Epidemiology, University Duisburg-Essen, D-45147 Essen, Germany.
  • Priebe L; 1] Institute of Human Genetics, University of Bonn, D-53127 Bonn, Germany [2] Department of Genomics, Life & Brain Center, University of Bonn, D-53127 Bonn, Germany.
  • Czerski PM; Department of Psychiatry, Poznan University of Medical Sciences, Poznan PL-60-572, Poland.
  • Hauser J; Department of Psychiatry, Poznan University of Medical Sciences, Poznan PL-60-572, Poland.
  • Lissowska J; Department of Cancer Epidemiology and Prevention, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw PL-02-781, Poland.
  • Szeszenia-Dabrowska N; Department of Epidemiology, Nofer Institute of Occupational Medicine, Lodz PL-91-348, Poland.
  • Brennan P; Genetic Epidemiology Group, International Agency for Research on Cancer (IARC), 69372 Lyon CEDEX 08, France.
  • McKay JD; Genetic Cancer Susceptibility Group, International Agency for Research on Cancer (IARC), 69372 Lyon CEDEX 08, France.
  • Wright A; 1] School of Psychiatry, University of New South Wales, Randwick, New South Wales 2052, Australia [2] Black Dog Institute, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia.
  • Mitchell PB; 1] School of Psychiatry, University of New South Wales, Randwick, New South Wales 2052, Australia [2] Black Dog Institute, Prince of Wales Hospital, Randwick, New South Wales 2031, Australia.
  • Fullerton JM; 1] Neuroscience Research Australia, Randwick, Sydney, New South Wales 2031, Australia [2] School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, New South Wales 2052, Australia.
  • Schofield PR; 1] Neuroscience Research Australia, Randwick, Sydney, New South Wales 2031, Australia [2] School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, New South Wales 2052, Australia.
  • Montgomery GW; Queensland Institute of Medical Research (QIMR), Brisbane, Queensland 4006, Australia.
  • Medland SE; Queensland Institute of Medical Research (QIMR), Brisbane, Queensland 4006, Australia.
  • Gordon SD; Queensland Institute of Medical Research (QIMR), Brisbane, Queensland 4006, Australia.
  • Martin NG; Queensland Institute of Medical Research (QIMR), Brisbane, Queensland 4006, Australia.
  • Krasnow V; Moscow Research Institute of Psychiatry, Moscow 107258, Russian Federation.
  • Chuchalin A; Institute of Pulmonology, Russian State Medical University, Moscow 105077, Russian Federation.
  • Babadjanova G; Institute of Pulmonology, Russian State Medical University, Moscow 105077, Russian Federation.
  • Pantelejeva G; Russian Academy of Medical Sciences, Mental Health Research Center, Moscow 115522, Russian Federation.
  • Abramova LI; Russian Academy of Medical Sciences, Mental Health Research Center, Moscow 115522, Russian Federation.
  • Tiganov AS; Russian Academy of Medical Sciences, Mental Health Research Center, Moscow 115522, Russian Federation.
  • Polonikov A; Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, Kursk 305041, Russian Federation.
  • Khusnutdinova E; Institute of Biochemistry and Genetics, Ufa Scientific Center of Russian Academy of Sciences, Ufa 450054, Russian Federation.
  • Alda M; 1] Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada B3H 2E2 [2] The International Group for the Study of Lithium-Treated Patients (IGSLI), Berlin, Germany.
Nat Commun ; 5: 3339, 2014 Mar 11.
Article em En | MEDLINE | ID: mdl-24618891
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Estudo de Associação Genômica Ampla Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Estudo de Associação Genômica Ampla Idioma: En Ano de publicação: 2014 Tipo de documento: Article