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Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists.
Ye, Xiang-Yang; Morales, Christian L; Wang, Ying; Rossi, Karen A; Malmstrom, Sarah E; Abousleiman, Mojgan; Sereda, Larisa; Apedo, Atsu; Robl, Jeffrey A; Miller, Keith J; Krupinski, John; Wacker, Dean A.
Afiliação
  • Ye XY; Department of Chemistry, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States. Electronic address: xiang-yang.ye@bms.com.
  • Morales CL; Department of Chemistry, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Wang Y; Department of Chemistry, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Rossi KA; CADD, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Malmstrom SE; Leads Discovery and Optimization, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Abousleiman M; Leads Discovery and Optimization, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Sereda L; Department of Biology, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Apedo A; Bioanalytical and Discovery Analytical Sciences, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Robl JA; Department of Chemistry, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Miller KJ; Department of Biology, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Krupinski J; Department of Biology, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
  • Wacker DA; Department of Chemistry, Research & Development, Bristol-Myers Squibb Co., PO Box 5400, Princeton, NJ 08543, United States.
Bioorg Med Chem Lett ; 24(11): 2539-45, 2014 Jun 01.
Article em En | MEDLINE | ID: mdl-24755425
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2014 Tipo de documento: Article