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5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation.
Hon, Gary C; Song, Chun-Xiao; Du, Tingting; Jin, Fulai; Selvaraj, Siddarth; Lee, Ah Young; Yen, Chia-An; Ye, Zhen; Mao, Shi-Qing; Wang, Bang-An; Kuan, Samantha; Edsall, Lee E; Zhao, Boxuan Simen; Xu, Guo-Liang; He, Chuan; Ren, Bing.
Afiliação
  • Hon GC; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Song CX; Department of Chemistry and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA.
  • Du T; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Jin F; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Selvaraj S; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Lee AY; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Yen CA; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Ye Z; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Mao SQ; State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Wang BA; State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Kuan S; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Edsall LE; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA.
  • Zhao BS; Department of Chemistry and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA.
  • Xu GL; State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • He C; Department of Chemistry and Institute for Biophysical Dynamics, Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA. Electronic address: chuanhe@uchicago.edu.
  • Ren B; Ludwig Institute for Cancer Research, La Jolla, CA 92093-0653, USA; Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, and Moores Cancer Center, University of California, San Diego School of Medicine, La Jolla, CA 92093. Electronic address: biren@ucsd.edu.
Mol Cell ; 56(2): 286-297, 2014 Oct 23.
Article em En | MEDLINE | ID: mdl-25263596
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Proteínas Proto-Oncogênicas / Elementos Facilitadores Genéticos / Metilação de DNA / Proteínas de Ligação a DNA Idioma: En Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Proteínas Proto-Oncogênicas / Elementos Facilitadores Genéticos / Metilação de DNA / Proteínas de Ligação a DNA Idioma: En Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos